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5-Lipoxygenase Deficiency Impairs Innate and Adaptive Immune Responses during Fungal Infection
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
5-lipoxygenase-derived products have been implicated in both the inhibition and promotion of chronic infection. Here, we sought to investigate the roles of endogenous 5-lipoxygenase products and exogenous leukotrienes ...
Murine macrophages cultured with IL-4 acquire a phenotype similar to that of epithelioid cells from granulomatous inflammation
(Kluwer Academic/plenum Publ, 2003-08-01)
Epithelioid cells (ECs) found in granulomas are thought to derive from mononuclear phagocytes. Although GM-CSF and/or IL-4 are known to promote cell differentiation their role in the development of ECs has never been ...
The possible role of a bacterial aspartate β-decarboxylase in the biosynthesis of alamandine
The understanding of the renin-angiotensin system (RAS) has significantly expanded over the last two decades.
The elucidation of angiotensin-converting enzyme 2 (ACE2) that converts angiotensin (Ang) II into Ang (1–7) ...
Analysis of the expression of toll-like receptors 2 and 4 and cytokine production during experimental Leishmania chagasi infection
(Instituto Oswaldo Cruz, Ministério da Saúde, 2011-08-01)
Toll-like receptors (TLRs) recognise pathogen-derived molecules and influence immunity to control parasite infections. This study aimed to evaluate the mRNA expression of TLRs 2 and 4, the expression and production of the ...
Effects of the solubility of yeast cell wall preparations on their potential prebiotic properties in dogs
(2019-11-01)
Derivatives of yeast cell wall (YCW) have been studied for their potential prebiotic effects. Recently, new purified and soluble preparations have been developed in an attempt to increase their biological actions. Two YCW ...
Chitosan-collagen scaffolds can regulate the biological activities of adipose mesenchymal stem cells for tissue engineering
(2013)
Scaffolds of chitosan and collagen can offer a biological niche for the growth of adipose derived stem cells (ADSC). The objective of this work was to characterize the physico-chemical properties of the scaffolds and the ...
Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its Gastroprotective Effect in Mouse Model
(2015)
Ten known meroterpenoids and the new meroterpenoid 7 were isolated from the Chilean seaweed Stypopodium flabelliforme as their acetylated derivatives. Furthermore, the known metabolite taondiol has been isolated for the ...
Gastroprotective effects of hydroethanolic root extract of Arrabidaea brachypoda: Evidences of cytoprotection and isolation of unusual glycosylated polyphenols
(2017-03-01)
The hydroethanolic root extract of Arrabidaea brachypoda, from Bignoniaceae family, a Brazilian medicinal plant, demonstrated significant in vivo gastroprotective effects using different in vivo assays. The activity was ...
Disfunción endotelial como alteración primaria en las patologías vasculares
(Sociedad Médica de Santiago, 2000)