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In situ gelling hexagonal phases for sustained release of an anti-addiction drug
(ELSEVIER SCIENCE BV, 2011)
In this study, fluid precursor formulations for subcutaneous injection and in situ formation of hexagonal phase gels upon water absorption were developed as a strategy to sustain the release of naltrexone, a drug used for ...
Ensaio clínico duplo-cego randomizado e placebocontrolado com naltrexona e intervenção breve no tratamento ambulatorial da dependência de álcool
(Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro, 2009-01-01)
OBJECTIVE: The objective of this study is to evaluate the efficacy of naltrexone with brief intervention among patients with alcohol dependence. METHOD: This study is a 12-week randomized, double blind, placebo-controlled ...
Estudo da influência dos ácidos graxos poli-insaturados na dependência e no craving pelo álcool
(Universidade Federal de São Paulo (UNIFESP), 2011-11-24)
Introdução: A fração lipídica das membranas celulares consiste de ácidos graxos poliinsaturados (PUFAS) e o uso crônico do álcool altera sua composição, modificando a permeabilidade. Portanto, a administração de PUFAS pode ...
Open elevated plus maze-induced antinociception in rats: A non-opioid type of pain inhibition?
(Pergamon-Elsevier B.V. Ltd, 2009-03-02)
CORNELIO, A. M. and NUNES-DE-SOUZA, R. L Open elevated plus maze-induced antinociception in rats: A non-opioid type of pain inhibition? PHYSIOL BEHAV 00 (0) 000-000, 2008. This study investigated whether antinociception ...
Open elevated plus maze-induced antinociception in rats: A non-opioid type of pain inhibition?
(Pergamon-Elsevier B.V. Ltd, 2009-03-02)
CORNELIO, A. M. and NUNES-DE-SOUZA, R. L Open elevated plus maze-induced antinociception in rats: A non-opioid type of pain inhibition? PHYSIOL BEHAV 00 (0) 000-000, 2008. This study investigated whether antinociception ...
BUPROPION/NALTREXONE FIXED-DOSE COMBINATION FOR THE TREATMENT OF OBESITY
(PROUS SCIENCE, SA-THOMSON REUTERS, 2011)
The combination of bupropion and naltrexone is one of the most promising new possibilities for the treatment of obesity in an era of increasing prevalence of this disease and decreasing options for its pharmacological ...
V1b Receptor Antagonist SSR149415 and Naltrexone Synergistically Decrease Excessive Alcohol Drinking in Male and Female Mice
(Wiley Blackwell Publishing, Inc, 2018-01)
Background: A recent clinical trial found that pharmacological blockade of V1b receptors reduces alcohol relapse in alcohol-dependent patients. SSR149415 is a selective V1b receptor antagonist that has potential for ...
Open elevated plus maze-induced antinociception in rats: A non-opioid type of pain inhibition?
(Pergamon-Elsevier B.V. Ltd, 2014)
Tratamento farmacológico da dependência do álcool
(Associação Brasileira de Psiquiatria - ABP, 2004-05-01)
The pharmacological intervention can play a crucial role in the reduction of craving and drinking and the maintenance of abstinence. This article reviews pharmacotherapy for alcohol dependence with an emphasis on the ...