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Enterolobium contortisiliquum Trypsin Inhibitor (EcTI), a Plant Proteinase Inhibitor, Decreases in Vitro Cell Adhesion and Invasion by Inhibition of Src Protein-Focal Adhesion Kinase (FAK) Signaling Pathways
(Amer Soc Biochemistry Molecular Biology Inc, 2012-01-02)
Tumor cell invasion is vital for cancer progression and metastasis. Adhesion, migration, and degradation of the extracellular matrix are important events involved in the establishment of cancer cells at a new site, and ...
Local and Relayed Effects of Deep Brain Stimulation of the Pedunculopontine Nucleus
(Molecular Diversity Preservation International, 2019-03)
Our discovery of low-threshold stimulation-induced locomotion in the pedunculopontine nucleus (PPN) led to the clinical use of deep brain stimulation (DBS) for the treatment of disorders such as Parkinson's disease (PD) ...
Structural features affecting trafficking, processing, and secretion of Trypanosoma cruzi mucins
(American Society for Biochemistry and Molecular Biology, 2012-07)
Trypanosoma cruzi is wrapped by a dense coat of mucin-type molecules encoded by complex gene families termedTcSMUG and TcMUC, which are expressed in the insect- and mammal-dwelling forms of the parasite, respectively. Here, ...
Phospholipid arachidonic acid remodeling during phagocytosis in mouse peritoneal macrophages
(Molecular Diversity Preservation International, 2020-08)
Macrophages contain large amounts of arachidonic acid (AA), which distributes differentially across membrane phospholipids. This is largely due to the action of coenzyme A-independent transacylase (CoA-IT), which transfers ...
The structure of the elicitor Cerato-platanin (CP), the first member of the CP fungal protein family, reveals a double ψβ-barrel fold and carbohydrate binding
(American Society For Biochemistry And Molecular Biology, 2011)
Cerato-platanin (CP) is a secretion protein produced by the fungal pathogen Ceratocystis platani, the causal agent of the plane canker disease and the first member of the CP family. CP is considered a pathogen-associated ...
Trypanosoma cruzi arginine kinase characterization and cloning. A novel energetic pathway in protozoan parasites
(American Society for Biochemistry and Molecular Biology, 2000-01)
This work contains the first description of a guanidino kinase in a flagellar unicellular parasite. The enzyme phosphorylates L-arginine and was characterized in preparations from Trypanosoma cruzi, the ethiological agent ...
Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat
(2002)
Purpose: We performed spinal implantation of olfactory ensheathing cells to demonstrate dorsal root afferent regeneration as well as bladder activity restoration after lumbosacral L6 to S2 rhizotomy. Materials and Methods: ...
Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat
(2002)
Purpose: We performed spinal implantation of olfactory ensheathing cells to demonstrate dorsal root afferent regeneration as well as bladder activity restoration after lumbosacral L6 to S2 rhizotomy. Materials and Methods: ...
Proteome and phosphoproteome of Africanized and European honeybee venoms
(2013-09-01)
Honey bee venom toxins trigger immunological, physiological, and neurological responses within victims. The high occurrence of bee attacks involving potentially fatal toxic and allergic reactions in humans and the prospect ...
Caracterização e análise da região codificadora do gene fruitless em moscas-das-frutas (Anastrepha obliqua)
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEvCâmpus São Carlos, 2011-10-28)
The fruit flies (Anastrepha sp) are organisms endemic to the Neotropics that are similar
morphologically but present some behavioral, reproductive and molecular variations. Among these
insects we can highlight the ...