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Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates
(2008)
Background: Prostate cancer is a leading cause of death in the male population, therefore, a comprehensive study about the genes and the molecular networks involved in the tumoral prostate process becomes necessary. In ...
New insights into the molecular basis of induced resistance triggered by potassium phosphite in potato
(2019-11-12)
This work aimed to provide data about the molecules involved in induced resistance mediated by potassium
phosphite (KPhi) in potato. To achieve these, we performed microarray analysis to determine the changes in
gene ...
Transcriptome changes in grapevine (Vitis viniferaL.) cv. Malbec leaves induced by ultraviolet-B radiation
(2010-10)
Ultraviolet-B radiation (UV-B, 280-315 nm) is a natural component of sunlight, which has numerous regulatory effects on plant physiology. The nature of the response to UV-B is dependent on fluence rate, dose, duration and ...
Transgenic expression of tobacco mosaic virus capsid and movement proteins modulate plant basal defense and biotic stress responses in Nicotiana tabacum
(2012)
Plant viruses cause metabolic and physiological changes
associated with symptomatic disease phenotypes. Symptoms involve direct and indirect effects, which result in disruption
of host physiology. We used transgenic ...
Estandarización y optimización de protocolos inmunohistoquímicos mediante la utilización de controles generados por micromatrices de tejido, elaborados para el Servicio de Anatomía del Hospital Dr. Gustavo Fricke
(Universidad de Valparaíso, 2013)
Durante años se ha tratado de objetivar el diagnóstico inmunohistoquímico, sin embargo, la carencia de recursos suficientes provoca que se deje de lado el mejor método para alcanzar una interpretación uniforme, los controles. ...
Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer
(2015)
Abstract
Background
Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack of reliable biomarkers for early diagnosis and limited targeted ...
CORAZON: a web server for data normalization and unsupervised clustering based on expression profiles
(BMC, 2020)
Objective Data normalization and clustering are mandatory steps in gene expression and downstream analyses, respectively. However, user-friendly implementations of these methodologies are available exclusively under expensive ...
Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells
(The Royal Society Publishing, 2017)
The hallmark of high-risk human papillomavirus (HR-HPV)-related carcinogenesis is E6 and E7 oncogene overexpression. The aim of this work was to characterize epithelial oral and cervical cancer cells that express HR-HPV ...
Increased SNAIL expression and low syndecan levels are associated with high Gleason grade in prostate cancer
(Oxford University Press, 2014)
Prostate cancer (PC) is a leading male oncologic malignancy wideworld. During malignant transformation, normal epithelial cells undergo genetic and morphological changes known as epithelial-mesenchymal transition (EMT). ...
A non-genomic signaling pathway shut down by mating changes the estradiol-induced gene expression profile in the rat oviduct
(Society for Reproduction and Fertility, 2010)
Estradiol (E2) accelerates oviductal egg transport through intraoviductal non-genomic pathways in unmated rats and through genomic
pathways in mated rats. This shift in pathways has been designated as intracellular path ...