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In vitro cytotoxic, antifungal, trypanocidal and leishmanicidal activities of acetogenins isolated from Annona cornifolia A. St. -Hil. (Annonaceae)
(Academia Brasileira de Ciências, 2015)
In vitro cytotoxic, antifungal, trypanocidal and leishmanicidal activities of acetogenins isolated from Annona cornifolia A. St. -Hil. (Annonaceae)
(Academia Brasileira de Ciências, 2022)
Leishmanicidal activity of fractions rich in aporphine alkaloids from Amazonian Unonopsis species
(Soc Brasileira FarmacognosiaJoao PessoaBrazil, 2012)
In vitro and in vivo activity of benzo[ c ]phenanthridines against Leishmania amazonensis
(Georg Thieme Verlag, 2014)
Seven benzo[c]phenanthridines, synthetic or isolated from Zanthoxylum rhoifolium root bark, were evaluated against Leishmania amazonensis axenic amastigotes. Five of them were considered leishmanicidal, with IC50 values ...
Leishmanicidal activity of Brosimum glaziovii (Moraceae) and chemical composition of the bioactive fractions by using high-resolution gas chromatography and GC-MS
(Sociedade Brasileira de Química, 2014-10-01)
As part of our ongoing SisBiota CNPq/FAPESP and Biota-FAPESP bioprospecting programs, this paper deals with the leishmanicidal properties of Brosimum glaziovii (Moraceae), and used gas chromatography analysis to determine ...
N, N′ N″-trisubstituted guanidines: Synthesis, characterization and evaluation of their leishmanicidal activity
(2019-06-01)
Leishmaniasis is a group of diseases caused by protozoan parasites from the genus Leishmania. There are estimated 1.3 million new cases annually with a mortality of 20,000–30,000 per year, when patients are left untreated. ...
Synthesis, Antitubercular and Leishmanicidal Evaluation of Resveratrol Analogues
(Soc Brasileira Quimica, 2016-12-01)
In this paper we continue our efforts in the search for new Schiff bases as resveratrol analogues as promising antitubercular and antileishmanial agents. Compounds were evaluated in vitro against Mycobacterium tuberculosis ...
Isolation, leishmanicidal evaluation and molecular docking simulations of piperidine alkaloids from Senna spectabilis
(Elsevier B.V., 2018-12-01)
Leishmaniasis is one of the most important neglected tropical diseases (NTDs) that are especially common among low-income populations in developing regions of Africa, Asia, and the Americas. Many natural products, particularly ...