Buscar
Mostrando ítems 311-320 de 449
Design and development of a novel supportive care product for the treatment of sialorrhea in Parkinson's disease
(Bentham Science Publishers, 2015-03)
Sialorrhea or excessive drooling is a significant medical issue in Parkinson’s disease (PD) and neurodegenerative disorders, although it is often underreported by patients. Sialorrhea affects a large proportion of PD ...
Targeting stress pathways to treat neurological disorders linked to protein misfoldingProtein Misfolding
(O'Doherty, C. B.Byrne, A. C. Nova Science, 2020)
Calidad de vida de pacientes con disfagia como consecuencia de trastornos del movimiento de origen neurológico
(Universidad de Chile, 2015)
Los Trastornos del Movimiento (TM) son enfermedades que se caracterizan por presentar alteración en la ejecución de los movimientos, cuya causa se debe a un daño en el Sistema Nervioso Central (SNC). La Enfermedad de ...
Disease-associated CAG·CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion
(Nucleic Acids Research 42(11) p. 7047–7056, 2014-05-01)
Genetically unstable expanded CAG·CTG trinucleotide repeats are causal in a number of human disorders, including Huntington disease and myotonic dystrophy type 1. It is still widely assumed that DNA polymerase slippage ...
Disease-associated CAG·CTG triplet repeats expand rapidly in non-dividing mouse cells, but cell cycle arrest is insufficient to drive expansion
(Nucleic Acids Research 42(11) p. 7047–7056, 2014-05-01)
Genetically unstable expanded CAG·CTG trinucleotide repeats are causal in a number of human disorders, including Huntington disease and myotonic dystrophy type 1. It is still widely assumed that DNA polymerase slippage ...
Modelos animais de disfunção colinérgica: papel da acetilcolina na cognição
(Universidade Federal de Minas GeraisUFMG, 2010-12-06)
The release of the neurotransmitter acetylcholine (ACh) depends on the vesicular loading by the vesicular acetylcholine transporter (VAChT). ACh is important for different cognitive functions such as learning, memory and ...
Memantina reduz o dano oxidativo em regiões cerebrais e melhora a memória de reconhecimento de longa duração em ratos velhos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2007)
Many neurodegenerative diseases, including Alzheimer’s (AD), Parkinson’s (PD) and Huntington’s diseases (HD), are caused by different mechanisms but may share a final common pathway to neuronal injury as a result of the ...
Memantina reduz o dano oxidativo em regiões cerebrais e melhora a memória de reconhecimento de longa duração em ratos velhos
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2007)
Many neurodegenerative diseases, including Alzheimer’s (AD), Parkinson’s (PD) and Huntington’s diseases (HD), are caused by different mechanisms but may share a final common pathway to neuronal injury as a result of the ...
Curcumin requires tumor necrosis Factor α signaling to alleviate cognitive impairment elicited by Lipopolysaccharide
(KargerBasel, 2013)
A decline in cognitive ability is a typical feature of the normal aging process, and of neurodegenerative disorders such as Alzheimer’s, Parkinson’s and Huntington’s diseases. Although their etiologies differ, all of these ...
The role of nicotinic cholinergic neurotransmission in delusional thinking
(Nature Publishing Group, 2020-12)
Delusions are a difficult-to-treat and intellectually fascinating aspect of many psychiatric illnesses. Although scientific progress on this complex topic has been challenging, some recent advances focus on dysfunction in ...