Buscar
Mostrando ítems 4111-4120 de 9114
5-HT1A receptors of the lateral septum regulate inhibitory avoidance but not escape behavior in rats
(Elsevier B.V., 2008-05-01)
Serotonin in the lateral septum (LS) has been implicated in the modulation of defensive behaviors and in anxiety. However, it is currently unknown whether changes in 5-HT mechanisms in this brain area may selectively affect ...
Duração e eficácia do efeito de diferentes anestésicos no bloqueio do nervo digital palmar em equinos
(Universidade Federal de Santa MariaBRMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina Veterinária, 2015-02-20)
The objective of the present study was to determine the duration and efficacy of local analgesia produced by bupivacaine, lidocaine and ropivacaine used to block the palmar digital (PD) nerve. Nine adult horses underwent ...
Efeitos da N-acetilcisteína sobre o dano oxidativo renal e hepático de ratos diabéticos
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2010-10-22)
Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia, which is related to oxidative stress and plays an important role in the development of other diseases and tissue damage, such as liver and kidney ...
Acute glucocorticoid effects on the multicomponent model of working memory
(Wiley-Blackwell, 2011-10-01)
Objective in comparison with basal physiological levels, acute, high levels of cortisol affect learning and memory. Despite reports of cortisol-induced episodic memory effects, no study has used a comprehensive battery of ...
Effects of acute and long-term typical or atypical neuroleptics on morphine-induced behavioural effects in mice
(Wiley-Blackwell, 2014-03-01)
<list list-type=1 id=cep12203-list-0001> It has been suggested that the high prevalence of drug abuse in schizophrenics is related to chronic treatment with typical neuroleptics and dopaminergic supersensitivity that ...
Avaliação dos mecanismos envolvidos na ação antinociceptiva causada pelo seleneto vinílico bis substituído (SVBS) em camundongos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2009-03-24)
The interest in organoselenium biochemistry and pharmacology has increased in the last two decades due to a variety of organoselenium compounds that possess biological activity. Accordingly, bis selenide is known as a safe ...
Individual Differences in Ethanol Locomotor Sensitization Are Associated with Dopamine D1 Receptor Intra-Cellular Signaling of DARPP-32 in the Nucleus Accumbens
(Public Library Science, 2014-06-11)
In mice there are clear individual differences in the development of behavioral sensitization to ethanol, a progressive potentiation of its psychomotor stimulant effect. Variability in the behavioral responses to ethanol ...
Successful Intra-arterial Thrombolysis in a Patient with an Intracranial Meningioma
(Elsevier B.V., 2013-11-01)
Alteplase (recombinant tissue plasminogen activator [rt-PA]) label approval by the Food and Drug Administration remarks the contraindication of its use with known intracranial neoplasm because of potential bleeding ...
Relative bioavailability study of two oral formulations of mycophenolate mofetil in healthy volunteers Estudio de biodisponibilidad relativa entre dos formulaciones orales de micofenolato mofetilo en voluntarios sanos
(2011)
Background: The bioequivalence of different formulations of a same pharmaceutical product must be tested empirically. Aim: To evaluate the relative bioavailability for an oral formulation of mycophenolate mofetil (MMF) ...
Noradrenaline acting at central ?-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration
Evidence indicates that the monoamine neurotransmitter noradrenaline elicits anti-inflammatory actions in the central nervous system (CNS), and consequently may play a neuroprotective role where inflammatory events contribute ...