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Full-term pregnancy induces a specific genomic signature in the human breast
(American Association for Cancer Research, 2008-01-16)
Breast cancer riskhas traditionally been linked to nulliparity or late first full-term pregnancy, whereas young age at first childbirth, multiparity, and breastfeeding are associated with a reduced risk. Early pregnancy ...
A suppressive antagonism evidences Progesterone and Estrogen receptor pathway interaction with concomitant regulation of Hand2, Bmp2 and ERK during early decidualization
(Public Library Of Science, 2015-04-21)
Progesterone receptor and estrogen receptor participate in growth and differentiation of the different rat decidual regions. Steroid hormone receptor antagonists were used to study steroid regulation of decidualization. ...
Tamoxifen down-regulates CD36 messenger RNA levels in normal and neoplastic human breast tissues
(Amer Assoc Cancer Research, 1997-02-01)
Tamoxifen (TAM) exerts a long-term suppressive effect on human breast cancer cell proliferation on. To determine whether the effects of TAM are mediated by specific gene activation or repression, normal and tumoral human ...
Processamento digital de fotografias a curta distância, na diferenciação quantitativa de manchas de pele
(Universidade Federal de Santa MariaBRGeociênciasUFSMPrograma de Pós-Graduação em Geomática, 2010-07-17)
The skin cancer is the abnormal and uncontrolled growth of the cells that compose the skin, disposing in formats different from borders, colors, sizes and symmetry creating different types. In general lines, the forms of ...
Slight temperature changes cause rapid transcriptomic responses in Trypanosoma cruzi metacyclic trypomastigotes.
BACKGROUND: Severe changes in temperature can affect the behavior and ecology of some infectious agents. Trypanosoma cruzi is a protozoan that causes Chagas disease. This parasite has high genetic variability and can be ...
Slight temperature changes cause rapid transcriptomic responses in Trypanosoma cruzi metacyclic trypomastigotes
Background: Severe changes in temperature can affect the behavior and ecology of some infectious agents. Trypanosoma cruzi is a protozoan that causes Chagas disease. This parasite has high genetic variability and can be ...
Endosulfan alters myometrial adaptation during early pregnancy and labor in neonatally exposed rats
(Elsevier, 2019)
Proper myometrial adaptation during gestation is crucial for embryo implantation, pregnancy maintenance and parturition. Abnormal myometrial differentiation or contractility might promote several reproductive disorders ...
Programming of the reproductive axis by hormonal and genetic manipulation in mice
(BioScientifica, 2018-06)
In mammals, the reproductive function is controlled by the hypothalamic-pituitary-gonadal axis. During development, mechanisms mediated by gonadal steroids exert an imprinting at the hypothalamic-pituitary level, by ...
Matrix Vesicles are carriers of Bone Morphogenetic Proteins (BMPs),
(Springer Tokyo, 2008-12)
Matrix vesicles (MVs) are well-positioned in the growth plate to serve as a carrier of morphogenetic information to nearby chondrocytes and osteoblasts. Bone morphogenetic proteins (BMPs), carried in MVs could promote ...
Estudo do genoma funcional de Corynebacterium pseudotuberculosis através de diferentes estratégias proteômicas
(Universidade Federal de Minas GeraisUFMG, 2015-03-11)
Corynebacterium pseudotuberculosis is a facultative intracellular pathogenic species, subdivided into two biovars: C. pseudotuberculosis ovis, etiologic agent of caseous lymphadenitis in small ruminants, and C. pseudotuberculosis ...