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Chemoenzymatic synthesis and biological evaluation of 2- and 3-hydroxypyridine derivatives against Leishmania mexicana
(Pergamon-Elsevier Science Ltd, 2012-08)
A series of hydroxyalkyl and acyloxyalkyl derivatives of 2- and 3-hydroxypyridine was synthesized and their biological activity was evaluated as growth inhibitors of protozoan Leishmania mexicana. Thirty novel compounds ...
Regioselective enzymatic synthesis of estradiol 17-fatty acid esters
(Arkat USA, 2005-11)
A series of acyl esters of 3,17-β-estradiol has been prepared by an enzymatic methodology. Eleven 17-monoacyl products (five novel compounds) were obtained in a highly regioselective way by acylation of 3,17-β-estradiol ...
Banana flavor: insights into isoamyl acetate production
(Nova Science Publishers, 2011)
Isoamyl acetate is one of the most important flavor compounds used in food industries because of its characteristic banana flavor. The ester is used as a flavoring compound in many foods and drinks, such as honey, butterscotch, ...
Immobilized enzymes and their applications
(Elsevier, 2019)
The aim of enzyme immobilization is to develop a robust biocatalyst able to work under inonnative and harsh operational conditions with an extended lifetime. Biocatalyst immobilization can be defined as physical confinement ...
Cápsides virales como nanoacarreadores enzimáticos para quimioterapia
(Universidad Nacional Autónoma de México. Dirección General de Cómputo y de Tecnologías de Información y Comunicación. Revista Digital Universitaria, 2014-08-01)
La encapsulación de enzimas dentro de cápsides virales llamadas "virus-like particles" (VLPs) o dentro de otro tipo de cajas proteicas es un tema de rápido desarrollo debido a sus implicaciones en biocatálisis así como su ...
Oxidative functionalization of a halimane diterpenoid achieved by fungal transformation
(2019-05-01)
Regio and stereoselective activation of sp 3 C–H bonds remain one of the major advantages of biocatalysis over traditional chemocatalytic methods. Herein, we describe the oxy-functionalization of halimane diterpenoid 1 by ...
Biocatalytic benefits of immobilized Fusarium sp. (GFC) lipase from solid state fermentation on free lipase from submerged fermentation
(2020-05-01)
Lipases are promising tools for the synthesis of high value-added compounds and have traditionally been obtained from submerged fermentation processes (SmF). However, solid-state fermentation (SSF) allows linking the ...
Enhancing the Biocatalytic Activity of l -Asparaginase Using Aqueous Solutions of Cholinium-Based Ionic Liquids
(2019-12-16)
l-Asparaginase (ASNase) is a high value enzyme for the pharmaceutical and food industries. Although ionic liquids (ILs) have been recognized as promising solvents or additives for biocatalysis, there are very few studies ...
Glucuronidation of Methylated Quercetin Derivatives: Chemical and Biochemical Approaches
(2020-12-16)
Botanical supplements derived from grapes are functional in animal model systems for the amelioration of neurological conditions, including cognitive impairment. Rats fed with grape extracts accumulate 3′-O-methyl-querce ...
From dirt to industrial applications: Pseudomonas putida as a Synthetic Biology chassis for hosting harsh biochemical reactions
(2016-10)
The soil bacterium Pseudomonas putida is endowed with a central carbon metabolic network capable of fulfilling high demands of reducing power. This situation arises from a unique metabolic architecture that encompasses the ...