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Systemic and local toxicity assay of an aqueous extract of Larrea divaricata Cav.: role of NDGA
(Society of Pharmaceutical Sciences and Research, 2015-07)
Larrea divaricata Cav. (Zygophyllaceae) is an autochthonous plant of South America, widely distributed in Argentina. It is used in folk medicine as an anti-inflammatory drug. By other way, presents well documented antitumoral ...
Avaliação da contaminação aquática por fármacos utilizando análises ecotoxicológicas
(Universidade Federal de Minas GeraisUFMG, 2017-05-22)
Considerable quantities of different classes of drugs are consumed annually worldwide. After use, these compounds are partially metabolized and excreted. The drugs, once disposed of in a sewage treatment plant, can remain ...
Advances in sickle cell disease treatment: From drug discovery until the patient monitoring
(2011-04-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in last years few therapeutical sources are currently available. ...
Advances in sickle cell disease treatment: From drug discovery until the patient monitoring
(2011-04-01)
Sickle Cell Disease (SCD) is one of the most prevalent hematological diseases in the world. Despite the immense progress in molecular knowledge about SCD in last years few therapeutical sources are currently available. ...
In vitro antifungal activity of Myracrodruon urundeuva Allemao against human vaginal Candida species
(Acad Brasileira De Ciencias, 2017-01-01)
Myracrodruon urundeuva is a plant native to Brazil, which is used by the indigenous population for the treatment of candidiasis. The aims of this study were to evaluate the antifungal activity of extract against human ...
Ocular topotecan pharmacokinetics following topical administration to rabbits for diffused anterior retinoblastoma
(Pharmaceutical Press-Royal Pharmaceutical Society Great Britian, 2017-05)
Objectives: We characterized and compared the in-vivo absorption of topotecan into the aqueous humor after instillation of aqueous and ointment formulations. Methods: A lanolin/petrolatum ointment was used. New Zealand ...
Toxic effects of annonaceous acetogenins on Oncopeltus fasciatus
(Springer Heidelberg, 2008-06)
From an Argentine collection of Annona cherimolia and a Bolivian collection of Annona montana (Annonaceae), the acetogenins, squamocin, molvizarin, itrabin, almuñequin, cherimolin-1, annonacin, annonacin-A, densicomacin-1, ...
Analgesic-antiinflammatory properties of Proustia pyrifolia
(ELSEVIER IRELAND LTD, 2005-05-13)
The anti inflammatory (per os and topic) and analgesic (per os) properties of the aerial part of Proustia pyrifolia a species in danger of extinction were investigated, and the major. compound"s of two of its active extracts ...