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Lanthanum carbonate, like sevelamer-HCl, retards the progression of vascular calcification and atherosclerosis in uremic apolipoprotein E-deficient mice
(OXFORD UNIV PRESSOXFORD, 2012)
Atherosclerosis and vascular calcification (VC) progression in chronic kidney disease is favored by disturbances of mineral metabolism. We compared the effect of phosphate binder lanthanum (La) carbonate with sevelamer-HCl ...
F-18-FDG Uptake and Calcifications in the Thoracic Aorta on Positron Emission Tomography/Computed Tomography Examinations Frequency and Stability on Serial Scans
(Lippincott Williams & Wilkins, 2011-02-01)
Purpose: Vascular F-18-2-fluoro-2-deoxy-D-glucose (F-18-FDG) uptake has been suggested as a means of identifying metabolically active atheroma, whereas vascular calcification is accepted as an indicator of atherosclerosis. ...
Reduced calcification and osteogenic features in advanced atherosclerotic plaques of mice with macrophage-specific loss of TRPC3
(Elsevier Ireland, 2018-03)
Background and aims: Recent in vitro studies have showed that in macrophages, deletion of the non-selective Ca2+-permeable channel TRPC3 impairs expression of the osteogenic protein BMP-2. The pathophysiological relevance ...
Not all vascular smooth muscle cell exosomes calcify equally in chronic kidney disease
(Nature Publishing Group, 2018-02-01)
Prevention of medial calcification in patients with chronic kidney disease requires the maintenance of vascular smooth muscle cell fitness. To preserve viability under chronic kidney disease–induced stress, vascular smooth ...
Obesidad y aterosclerosis; principales factores de riesgo que desarrollan la Calcificación Cardiovascular
(2017-08-31)
Cardiovascular calcification has been observed in the vasculature of the arteries for
many decades, but recently, this phenomenon was seen simply as a passive
consequence of aging. Nowadays, the accumulation of evidence ...
Oxidant generation predominates around calcifying foci and enhances progression of aortic valve calcification
(LIPPINCOTT WILLIAMS & WILKINS, 2008)
Objective - We hypothesized that reactive oxygen species ( ROS) contribute to progression of aortic valve ( AV) calcification/ stenosis. Methods and Results - We investigated ROS production and effects of antioxidants ...
Rol de los fitoestrógenos en la calcificación vascular e interacciones óseo-vascularesRole of phytoestrogens in vascular calcification and bone-vascular interactions
(Asociación Argentina de Osteología y Metabolismo Mineral, 2020-08)
La osteoporosis y las enfermedades cardiovasculares son patologías prevalentes en mujeres posmenopáusicas. La calcificación vascular es un proceso en el que se produce una distorsión de la arquitectura natural del tejido ...