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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility
(Rockefeller Univ Press, 2013-09-23)
Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs). Here, we uncover a previously unappreciated role for the formin ...
Caracterização biológica e filogenética de uma amostra de Vaccinia virus silvestre - SPAn232 (SAV)
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em MicrobiologiaUFMG, 2019-03-18)
The SPAn232 virus (SPAnV) sample was isolated in the 1960s in the Cotia forest in the state of São Paulo during a government epidemiological surveillance program and was originally grouped as a Cotia virus (COTV - sample ...
Avaliação da circulação de Orthopoxvirus em pequenos mamíferos de áreas urbanas, silvestres e rurais de Minas Gerais, Brasil
(Universidade Federal de Minas GeraisUFMG, 2016-02-19)
Vaccinia virus causes in Brazil a disease named Bovine vaccine and it affects mainly milking cows and cow handlers. This disease causes many economic, social and public health losses. Virus circulation clues have been ...
A role for the small GTPase Rac1 in vaccinia actin-based motility
(Taylor & Francis, 2014-10-31)
Vaccinia virus dissemination relies on the recruitment of the nucleation promoting factor N-WASP underneath cell-associated extracellular virus (CEVs) and subsequent recruitment and activation of the ARP2/3 complex, a major ...
Infecções humanas causadas por poxvirus relacionados ao vírus vaccinia no Brasil
(Sociedade Brasileira de Medicina Tropical - SBMT, 2009)
A partir de 1999, infecções humanas por Orthopoxvirus vem sendo observadas em pelo menos oito estados no país, com a formação de vesículas as quais evoluem para pústulas e crostas, principalmente nos membros superiores e ...
Linfócitos T CD4+ e CD8+ participam da resposta imune de memória contra a infecção humana natural pelo vaccinia virus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2013-12-18)
The present study evaluates the immune response of memory CD4+ and CD8+ T cells from patients following a natural Vaccinia virus (VACV) infection. A total of 42 individuals were involved in the study being: 22 previously ...
Vaccinia virus: Detecção e viabilidade no leite de vacas experimentalmente inoculadas
(Universidade Federal de Minas GeraisUFMG, 2014-02-26)
Bovine vaccinia (VB) is an emerging zoonotic disease caused by Vaccinia virus (VACV), anOrthopoxvirus (OPV). The disease is characterized by the emergence of ulcerated lesions in theteats of dairy cows and in milkers hands ...
Perfil fenotípico das células NK em uma reexposição viral, in vitro, após uma infecção humana natural prévia pelo Vaccinia virus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2014-05-17)
Vaccinia virus (VACV) is the causative agent of a zoonotic infection that affects cattle and humans in many regions of Brazil. Little is known about the human immunological response against VACV natural infection, but it ...
Adverse Events Post Smallpox-Vaccination: Insights from Tail Scarification Infection in Mice with Vaccinia virus
(Public Library of Science, 2014)