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Risedronate transdermal delivery system based on a fumaric copolymer for therapy of osteoporosis
(Elsevier Science, 2017-07)
Transdermal drug delivery system (TDDS) could be seen as alternative to the oral administration which avoids several adverse effects. In this study a novel TDDS for risedronate (RI), a bisphosphonate used for osteoporosis ...
Layer-by-layer films containing emodin or emodin encapsulated in liposomes for transdermal applications
(2018-02-01)
Dermal drug release systems are an important area of research because they can be applied to the skin in a non-invasive procedure using a lower concentration of drugs. In this study, we have developed two types of ...
Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine
(2021-11-01)
Artemether (ART) and lumefantrine (LUM) are the gold standard antimalarial drugs used for the treatment of malaria in children and pregnant women. Typically, ART and LUM are delivered orally in the form of a combined tablet, ...
Rotigotine transdermal delivery for the treatment of Parkinson's disease
(Informa Healthcare, 2009-03)
Background: Rotigotine is a non-ergot dopamine agonist that has been developed as a new transdermal formulation, and is indicated for use in early (USA and Europe) and advanced (Europe only) Parkinson's disease (PD). The ...
Evaluation of skin absorption of drugs from topical and transdermal formulations
(Univ Sao Paulo, Conjunto Quimicas, 2016-07-01)
The skin barrier function has been attributed to the stratum corneum and represents a major challenge in clinical practice pertaining to cutaneous administration of drugs. Despite this, a large number of bioactive compounds ...
Transdermal delivery of methotrexate: iontophoretic delivery from hydrogels and passive delivery from microemulsions
(ELSEVIER SCIENCE BV, 2001)
In vitro assays were performed to investigate the effectiveness of transdermal administration of methotrexate (MTX) by iontophoretic delivery from two types of hydrogel and passive delivery from two types of microemulsion. ...
Physicochemical, In Vitro And In Vivo Evaluation Of Flurbiprofen Microemulsion
(ACAD BRASILEIRA DE CIENCIASRIO JANEIRO, 2015)