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Effect of human TGF-beta on the gene expression profile of Schistosoma mansoni adult worms
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
Schistosoma mansoni is responsible for schistosomiasis, a parasitic disease that affects 200 million people worldwide. Molecular mechanisms of host-parasite interaction are complex and involve a crosstalk between host ...
Epithelium and stroma from nasal polyp mucosa exhibits inverse expression of TGF- beta(1) as compared with healthy nasal mucosa
(Biomed Central Ltd, 2013-04-15)
Objective: To evaluate TGF-beta(1) expression in polypoid mucosa (epithelium and stroma) of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP).Methods: Cross-sectional study with two groups: 17 patients ...
Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production
(Landes Bioscience, 2014-01-01)
Integrin alpha v beta 3 is most likely the foremost modulator of angiogenesis among all known integrins. Recombinant disintegrin DisBa-01, originally obtained from snake venom glands, binds to alpha v beta 3, thereby ...
Participation of the SMAD2/3 signalling pathway in the down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ss1)
(2019)
Megalin/LRP2 is a receptor that plays important roles in the physiology of several organs, such as kidney, lung, intestine, and gallbladder and also in the physiology of the nervous system. Megalin expression is reduced ...
Expression of matrix metalloproteinases in cyclosporin-treated gingival fibroblasts is regulated by transforming growth factor (TGF)-beta 1 autocrine stimulation
(Amer Acad PeriodontologyChicagoEUA, 2002)
Interaction between the aryl hydrocarbon receptor and transforming growth factor-beta signaling pathways: evidence of an asymmetrical relationship in rat granulosa cells
(Elsevier, 2008-10)
The aryl hydrocarbon receptor (AHR) mediates toxic responses to environmental contaminants and plays pivotal physiological roles in various biological processes as well, particularly in ovarian function. It is well documented ...
CD4+FOXP3+cells produce IL-10 in the spleens of dogs with visceral leishmaniasis
(Elsevier B.V., 2014-05-28)
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect humans and several animal species. Dogs are one of the main urban reservoirs of the parasite and play a central role in ...
Influence of the photoperiod on TGF-β1 and p15 expression in hamster Leydig cells
(Inst Animal Reproduction Food Research, 2012-12)
Adult hamsters exposed to short photoperiods show a marked atrophy of their internal reproductive organs, including a reduction in size, though not number of Leydig cells. Transforming growth factor-β1 (TGF-β1) is involved ...
Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway
(JOHN WILEY & SONS LTD, 2009)
Common features such as elastic fibre destruction, mucoid accumulation, and smooth muscle cell apoptosis are co-localized in aneurysms of the ascending aorta of various aetiologies. Recent experimental studies reported an ...