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The involvement of TLR2 and TLR4 in cytokine and nitric oxide production in visceral leishmaniasis patients before and after treatment with anti-leishmanial drugs
(Public Library Science, 2015-02-23)
Toll-like receptors (TLRs) have significant involvement in Leishmania infection, although little is known about the relationship between these receptors, cytokines and nitric oxide (NO) in patients with visceral leishmaniasis ...
Role of TLR2 and TLR4 in Human Neutrophil Functions Against Paracoccidioides brasiliensis
(Wiley-Blackwell Publishing, Inc, 2010-02-01)
In paracoccidioidomycosis, a systemic mycosis caused by the fungus Paracoccidioides brasiliensis (Pb), studies have focused on the role of neutrophils that are involved in primary response to the fungus. Neutrophil functions ...
Role of TLR2 and TLR4 in Human Neutrophil Functions Against Paracoccidioides brasiliensis
(Wiley-Blackwell Publishing, Inc, 2010-02-01)
In paracoccidioidomycosis, a systemic mycosis caused by the fungus Paracoccidioides brasiliensis (Pb), studies have focused on the role of neutrophils that are involved in primary response to the fungus. Neutrophil functions ...
Papel dos receptores do tipo Toll endossomais na resistência à infecção por Toxoplasma gondii
(Universidade Federal de Minas GeraisUFMG, 2013-03-01)
Toxoplasma gondii is an obligate intracellular parasite belonging to the phylum apicomplexa and can virtually infect all warm-blood vertebrates. Although humans are considered accidental intermediate hosts, one third of ...
Molecular cloning of Salmo salar Toll-like receptors (TLR1, TLR22, TLR5M and TLR5S) and expression analysis in SHK-1 cells during Piscirickettsia salmonis infection
(2015)
In fish, the innate immune system is the primary response against infection. Toll-like receptors (TLRs) recognize pathogens through pathogen-associated molecular patterns (PAMPs), and some target molecules of TLRs are ...
Influence of TLR-2 in the immune response in the infection induced by fungus Sporothrix schenckii
(2014-01-01)
Toll-like receptors (TLRs) play an important role in immunity, since they bind to pathogen surface antigens and initiate the immune response. However, little is known about the role of TLR-2 in the recognition of S. schenckii ...
P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling
(2018-01-17)
Background: Toll-like receptors (TLRs) are transmembrane proteins expressed on the surface of ovarian cancer (OC) and immune cells. Identifying the specific roles of the TLR-mediated signaling pathways in OC cells is ...
TLR2- and 4-independent immunomodulatory effect of high molecular weight components from Ascaris suum
(Pergamon PressOxford, 2014-03)
Components of high molecular-weight (PI) obtained from Ascaris suum extract down-regulate the Th1/Th2-related immune responses induced by ovalbumin (OVA)-immunization in mice. Furthermore, the PI down-modulates the ability ...