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Helper Activity by Human Large Granular Lymphocytes in in Vitro Immunoglobulin Synthesis
(Journal of Clinical lmmunology, 2017)
Extracellular-regulated kinase and p38 mitogen-activated protein kinases are involved in the antiapoptotic action of 17β-estradiol in skeletal muscle cells
(BioScientifica, 2010-08)
17β-Estradiol (E2) stimulates the mitogen-activated protein kinases (MAPKs) in various cellular types.We have shown that the hormone activates extracellular-regulated kinase (ERK) and p38 MAPK in skeletal muscle cells. ...
Down-regulation of p38 mitogen-activated protein kinase activation and proinflammatory cytokine production by mitogen-activated protein kinase inhibitors in inflammatory bowel disease
(Wiley Blackwell Publishing, Inc, 2010-10)
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBD) characterized by chronic relapsing mucosal inflammation. Tumour necrosis factor (TNF)-α, a known agonist of the mitogen-activated protein kinase ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
(1986)
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
(1986)
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...
Foot-and-mouth disease virus infection of dendritic cells triggersphosphorylation of ERK1/2 inducing class I presentation and apoptosis
(Elsevier, 2015-07)
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. This pathol-ogy is caused by foot-and-mouth disease virus (FMDV). Over time, the development of vaccines to preventthe spread of ...
p38 MAPK regulates IL-1β induced IL-6 expression through mRNA stability in osteoblasts
(2004-06-08)
Osteoblast-derived IL-6 functions in coupled bone turnover by supporting osteoclastogenesis favoring bone resorption instead of bone deposition. Gene regulation of IL-6 is complex occurring both at transcription and ...
p38 MAPK regulates IL-1β induced IL-6 expression through mRNA stability in osteoblasts
(2004-06-08)
Osteoblast-derived IL-6 functions in coupled bone turnover by supporting osteoclastogenesis favoring bone resorption instead of bone deposition. Gene regulation of IL-6 is complex occurring both at transcription and ...
Effects of Euphorbia milii latex on mitogen-induced lymphocyte proliferationEfeito do latex de Euphorbia milii sobre a proliferação de linfócitos induzida por mitogénio
(Sociedade Brasileira de Plantas Medicinais, 2015)
Treatment with galectin-1 eye drops regulates mast cell degranulation and attenuates the severity of conjunctivitis
(2018-08-15)
Galectin-1 (Gal-1) is a β-galactoside-binding protein with diverse biological activities in the pathogenesis of inflammation, however the mechanisms by which Gal-1 modulates cellular responses in allergic inflammatory ...