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Mostrando ítems 41-50 de 1807
Landscape of the spliced leader trans-splicing mechanism in Schistosoma mansoni
(Nature Publishing Group, 2019)
Influencia de la elongación transcripcional sobre el splicing alternativoInfluence of transcriptional elongation on alternative splicing
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2004)
SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
(Oxford University Press, 2017-06)
Pre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us to explore ...
ASpli: integrative analysis of splicing landscapes through RNA-Seq assays
(Oxford University Press, 2021-03)
Genome-wide analysis of alternative splicing has been a very active field of research since the early days of Next Generation Sequencing technologies. Since then, ever-growing data availability and the development of ...
Light in the transcription landscape: chromatin, RNA polymerase II and splicing throughout Arabidopsis thaliana's life cycle
(Taylor & Francis, 2020-08)
Plants have a high level of developmental plasticity that allows them to respond and adapt to changes in the environment. Among the environmental cues, light controls almost every aspect of A. thaliana’s life cycle, including ...
Differential splicing analysis based on isoforms expression with NBSplice
(Academic Press Inc Elsevier Science, 2020-03)
Alternative splicing alterations have been widely related to several human diseases revealing the importance of their study for the success of translational medicine. Differential splicing (DS) occurrence has been mainly ...
A chromatin code for alternative splicing involving a putative association between CTCF and HP1aα proteins
(BioMed Central, 2015-12-02)
Background: Alternative splicing is primarily controlled by the activity of splicing factors and by the elongation of the RNA polymerase II (RNAPII). Recent experiments have suggested a new complex network of splicing ...
Estudio de la relación entre transcripción y Splicing alternativo de mRNAs eucarióticosAnalysis of the relationship between transcription and alternative splicing of eukaryotic mRNAs
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 1999)
Epigenetics at the base of alternative splicing changes that promote colorectal cancer
(American Society for Clinical Investigation, 2017-08)
Chromatin modification influences gene expression by either repressingor activating genes, depending on the specific histone mark. Chromatin structure can also influence alternative splicing of transcripts; however, the ...
Functional Characterization of NIPBL Physiological Splice Variants and Eight Splicing Mutations in Patients with Cornelia de Lange Syndrome
(Molecular Diversity Preservation International, 2014-05)
Cornelia de Lange syndrome (CdLS) is a congenital developmental disorder characterized by distinctive craniofacial features, growth retardation, cognitive impairment, limb defects, hirsutism, and multisystem involvement. ...