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Hipótesis del neurodesarrollo anormal en la esquizofrenia
(1997)
The neurodevelopmental hypothesis of schizophrenia states that the disease is associated with abnormal brain development. This defect predisposes to a characteristic pattern of brain malfunction in early adult fife and to ...
Schizophrenia, brain disease and meta-analyses: Integrating the pieces and testing Fusar-Poli`s hypothesis
(CHURCHILL LIVINGSTONE, 2010)
This paper aims to discuss and test the hypothesis raised by Fusar-Poli [Fusar-Poli P. Can neuroimaging prove that schizophrenia is a brain disease? A radical hypothesis. Medical Hypotheses in press, corrected proof] that ...
Autonomic nervous system activation during social cognition tasks in patients with schizophrenia and their unaffected relatives
(Lippincott Williams, 2011-12)
Objective: To determine if patients with schizophrenia and their unaffected first degree relatives have abnormal autonomic nervous system (ANS) responses to social cognition tasks. Background: Social cognition impairments ...
Emotion processing and theory of mind in schizophrenia patients and their unaffected first-degree relatives
(Elsevier, 2010-04)
Previous studies have suggested that social cognition is affected in individuals with schizophrenia. The purpose of this study was to explore to what extent social cognition deficits are shared by unaffected first-degree ...
Interneuron NMDA receptor ablation induces hippocampus-prefrontal cortex functional hypoconnectivity after adolescence in a mouse model of schizophrenia
(Society for Neuroscience, 2020-04)
Although the etiology of schizophrenia is still unknown, it is accepted to be a neurodevelopmental disorder that results from the interaction of genetic vulnerabilities and environmental insults. Although schizophrenia’s ...
Brain connectivity in patients with schizophrenia related to psychological stress
(Elsevier Masson, 2017)
Introduction It is commonly accepted that in most patients with schizophrenia external factors act on genetic predisposition to pro- duce active psychotic symptoms. In fact, we showed that patients with schizophrenia have ...
A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study
(Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study
(Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...