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Mostrando ítems 631-640 de 1393
The importance of glycine receptor clustering in the functional maturation of spinal synapses.
(Universidad de Concepción, Facultad de Ciencias Biológicas., 2002)
Considerando abundantes estudios bioquímicos e inmunocitoquímicos se ha generado un modelo que describe la estructura de la sinápsis glicinérgica en neuronas espinales. Así, se postula que el citoesqueleto, a través la ...
Molecular Imaging Genetics of Methylphenidate Response in ADHD and Substance Use Comorbidity
(Wiley-Blackwell, 2011-02-01)
Purpose: Attention-deficit/hyperactivity disorder (ADHD) and substance use disorders (SUDs) are highly comorbid and may share a genetic vulnerability. Methylphenidate (MPH), a dopamine transporter (DAT) blocker, is an ...
Alcohol neurotoxicityNeurotoxicidad alcohólicaNeurotoxicidade de álcool
(Universidad Militar Nueva Granada, 2017)
Synaptic plasticity alterations associated to memory impairment induced by deletion of CB2 cannabinoid receptor
(Elsevier, 2013-05)
In this study, the role of CB2r on aversive memory consolidation was further evaluated. Mice lacking CB2r (CB2KO) and their corresponding littermates (WT) were exposed to the step-down inhibitory avoidance test (SDIA). ...
Projeto preliminar do sistema de ancoragem de uma plataforma oceânica: validação e verificação de ferramentas computacionais
(Joinville, SC, 2022-07-25)
Desde sua descoberta até os dias atuais, o petróleo ocupa um importante papel na cadeia global de geração de energia. Dado que grande parte das reservas espalhadas pelo mundo estão situadas no leito dos oceanos, as plataformas ...
Presynaptic Cav2.1 calcium channels carrying a familial hemiplegic migraine mutation r192q allow faster recovery from syanptic depression in mouse calyx of held
(American Physiological Society, 2012-12)
CaV2.1 Ca2+ channels have a dominant and specific role in initiating fast synaptic transmission at central excitatory synapses, through a close association between release sites and calcium sensors. Familial hemiplegic ...
Rol del neuropéptido PDF en la adquisición y el mantenimiento de la estructura del circuito PDFRole of the PDF neuropeptide in the acquisition and maintenance of the PDF circuit structure
(2013-06)
La ritmicidad comportamental en Drosophila es sostenida por una red neuronal que en el cerebro adulto comprende alrededor de 150 neuronas. Entre éstas, las sLNv han demostrado ser esenciales para el control de la actividad ...
Análises de redes modulares de co-expressão gênica revelam vias importantes na doença de Alzheimer e paralisia supranuclear progressiva
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOINFORMÁTICA, 2021-09-28)
The incidence of neurodegenerative diseases leading to impairment of cognitive functions and
dementia have increased in recent years, mainly because of enhanced longevity in the
population worldwide. Understanding the onset ...
Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019)
Neurodegenerative and neuromuscular disorders can manifest throughout the lifespan of an individual, from infant to elderly individuals. Axonal and synaptic degeneration are early and critical elements of nearly all human ...