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Impaired HPA axis function in diabetes involves adrenal apoptosis and phagocytosis
(Humana Press, 2019-03)
Purpose: The aim of the present study was to analyze the involvement of oxidative stress and inflammation in the modulation of glucocorticoid production in the adrenal cortex of diabetic rats. Methods: Male Wistar rats ...
Thiol redox biochemistry: Insights from computer simulations
(Springer, 2014-03)
Thiol redox chemical reactions play a key role in a variety of physiological processes, mainly due to the presence of low-molecular-weight thiols and cysteine residues in proteins involved in catalysis and regulation. ...
Biomarkers of oxidative stress and endothelial dysfunction in glucose intolerance and diabetes mellitus
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Objectives: To evaluate biomarkers of endothelial dysfunction and oxidative stress in glucose intolerance (GI) compared to overt diabetes (DM2). Design and methods: 140 volunteers including 96 with DM2, 32 with GI and 12 ...
Nitrosative/Oxidative Stress Conditions Regulate Thioredoxin-Interacting Protein (TXNIP) Expression and Thioredoxin-1 (TRX-1) Nuclear Localization
(Public Library Science, 2013-12-20)
Thioredoxin (TRX-1) is a multifunctional protein that controls the redox status of other proteins. TRX-1 can be found in the extracellular milieu, cytoplasm and nucleus, and it has distinct functions in each environment. ...
The effect of nitric oxide on mitochondrial respiration
(Academic Press Inc Elsevier Science, 2019-07)
This article reviews the interactions between nitric oxide (NO)and mitochondrial respiration. Mitochondrial ATP synthesis is responsible for virtually all energy production in mammals, and every other process in living ...
El óxido nítrico y las especies reactivas de nitrógeno: aspectos básicos e importancia biológica.
(Facultad de Química de la Universidad Nacional Autónoma de México, 2006)
S-nitrosoglutathione Inhibits Inducible Nitric Oxide Synthase Upregulation By Redox Posttranslational Modification In Experimental Diabetic Retinopathy
(Association for Research in Vision and Ophthalmology Inc., 2014)
NO/H2S "crosstalk" Reactions. The Role of Thionitrites (SNO-) and Perthionitrites (SSNO-)
(American Chemical Society, 2019-11)
The redox chemistry of H2S with NO and other oxidants containing the NO group is discussed on a mechanistic basis because of the expanding interest in their biological relevance, with an eye open to the chemical differences ...