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Cardiac Thyrotropin-releasing Hormone Inhibition Improves Ventricular Function and Reduces Hypertrophy and Fibrosis After Myocardial Infarction in Rats
(Churchill Livingstone Inc Medical Publishers, 2021-07)
Background: Cardiac thyrotropin-releasing hormone (TRH) is a tripeptide with still unknown functions. We demonstrated that the left ventricle (LV) TRH system is hyperactivated in spontaneously hypertensive rats and its ...
Dynamic regulation of chromatin topology and transcription by inverted repeat-derived small RNAs in sunflower
(National Academy of Sciences, 2019-08)
Transposable elements (TE) are extremely abundant in complex plant genomes. Small interfering RNAs (siRNAs) of 24 nucleotides in length control transposon activity in a process that involves de novo methylation of targeted ...
The New World Of Rnas.
(2014)
The new world of RNAs
(Sociedade Brasileira de Genética, 2014)
In vivo therapeutic efficacy of TNF alpha silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice
(Dove Medical Press Ltd, 2018-01-01)
Background: Tumor necrosis factor-alpha (TNF alpha), a pro-inflammatory cytokine, has been shown to play a role in the pathophysiology of rheumatoid arthritis. Silencing TNFa expression with small interfering RNA (siRNA) ...
Análise da expressão gênica de pequenos RNAs derivados de tRNAs (tRFs) em plantas
(Universidade Estadual Paulista (Unesp), 2012)
Small non coding RNAs emerged as important characters in several biology aspects. Among then, the most studied are microRNAs (miRNAs) and short interfering RNAs (siRNAs), that regulate their target gene post-transcriptionally ...
CSDC2, a cold shock domain RNA-binding protein in decidualization
(Wiley-liss, Div John Wiley & Sons Inc, 2018-01)
RNA-binding proteins (RBPs) have been described for cancer cell progression and differentiation, although there is still much to learn about their mechanisms. Here, using in vivo decidualization as a model, we describe the ...