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Antileishmanial and antitrypanosomal activity of the cutaneous secretion of Siphonops annulatus
(BioMed Central, 2014)
Abstract
Background
Among the tropical parasitic diseases, those caused by protozoans are considered a challenge to public health, being represented by leishmaniasis and ...
A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cells
(BioMed Central, 2016)
Abstract
Background
Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative agent of bovine babesiosis, a potential risk ...
The exponential-Poisson model for recurrent event data: an application to a set of data on malaria in Brazil
(John Wiley and SonsMalden, Ma, 2015-03)
In this paper,we introduce a newmodel for recurrent event data characterized by a baseline rate function
fully parametric, which is based on the exponential-Poisson distribution. The model arises from a latent
competing ...
Influence of Ecto-Nucleoside Triphosphate Diphosphohydrolase Activity on Trypanosoma cruzi Infectivity and Virulence
(PUBLIC LIBRARY SCIENCE, 2009)
Background: The protozoan Trypanosoma cruzi is the causative agent of Chagas disease. There are no vaccines or effective treatment, especially in the chronic phase when most patients are diagnosed. There is a clear necessity ...
Molecular Modeling Suggests Cruzain Specificity for Peptide Primaquine Prodrugs
(BENTHAM SCIENCE PUBL LTD, 2010)
Chagas` disease, infection caused by the protozoan Trypanosoma cruzi, is an important, social and medical ailment in the Latin America. This disease is endemic in 21 countries, mostly Latin America countries, with more ...
Primeiro registro de Trypanosoma vivax em bovinos no Estado do Rio Grande do Sul, Brasil
(Universidade Federal de Santa Maria, 2009)
Este estudo teve o objetivo de relatar a ocorrência de Trypanosoma vivax no Sul do Brasil. O protozoário foi diagnosticado em esfregaço sanguíneo de um bovino e a identificação baseada na morfologia das formas tripomastigotas ...
A new thrombospondin-related anonymous protein homologue in Neospora caninum (NcMIC2-like1)
(CAMBRIDGE UNIV PRESS, 2011)
Neospora caninum is an Apicomplexan protozoan that has the dog as a definitive host and cattle (among other animals) as intermediate hosts. It causes encephalopathy in dogs and abortion in cows, with significant loss in ...
A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cells
(2016-11-14)
Abstract
Background
Babesia bovis is a tick-transmitted protozoan hemoparasite and the causative agent of bovine babesiosis, a potential risk to ...
Synergistic activity between statins and bisphosphonates against acute experimental toxoplasmosis
(American Society for Microbiology, 2017-08)
Bisphosphonates are widely used for the treatment of bone disorders. These drugs also inhibit the growth of a variety of protozoan parasites, such as Toxoplasma gondii, the etiologic agent of toxoplasmosis. The target of ...
Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion
(Public Library of Science, 2015-04)
Background: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets ...