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Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation
(1999-02-01)
Hrp1p is a heterogeneous ribonucleoprotein (hnRNP) from the yeast Saccharomyces cerevisiae that is involved in the cleavage and polyadenylation of the 3'-end of mRNAs and mRNA export. In addition, Hrp1p is one of several ...
Schistosoma mansoni encodes SMT3B and SMT3C molecules responsible for post-translational modification of cellular proteins
(ELSEVIER IRELAND LTD, 2008)
The sumoylation pathway is a post-translational modification of nuclear proteins widespread among several organisms. SMT3C is the main protein involved in this process and it is covalently conjugated to a diverse assortment ...
Sperm proteomics: potential impact on male infertility treatment
(Taylor & Francis Ltd, 2016)
Spermatozoa are unique cells that have highly compact DNA, motility (and hypermotility) patterns, a specific morphology, localized mitochondria and an apical acrosome. They are the end product of a dynamic process termed ...
Ablation of arginyl-tRNA-protein transferase in oligodendrocytes impairs central nervous system myelination
(Wiley-liss, div John Wiley & Sons Inc., 2021-10)
Addition of arginine (Arg) from tRNA can cause major alterations of structure and function of protein substrates. This post-translational modification, termed protein arginylation, is mediated by the enzyme arginyl-tRNA-protein ...
Effects of different PER translational kinetics on the dynamics of a Core Circadian Clock model
(Public Library Of Science, 2015-01-21)
Living beings display self-sustained daily rhythms in multiple biological processes, which persist in the absence of external cues since they are generated by endogenous circadian clocks. The period (per) gene is a central ...
Polysome-seq as a Measure of Translational Profile from Deoxyhypusine Synthase Mutant in Saccharomyces cerevisiae
(2020-01-01)
The profile of proteins observed in a cell is characterized by the control of gene expression, which has several regulation points acting individually or in concert, such as epigenetic, transcriptional, translational, ...
Detection of methylation, acetylation and glycosylation of protein residues by monitoring 13C chemical-shift changes: A quantum-chemical study
(PeerJ, 2016-06)
Post-translational modifications of proteins expand the diversity of the proteome by several orders of magnitude and have a profound effect on several biological processes. Their detection by experimental methods is not ...
Akt/PKB: one kinase, many modifications
(Portland Press, 2015-06)
Akt/PKB, a serine/threonine kinase member of the AGC family of proteins, is involved in the regulation of a plethora of cellular processes triggered by a wide diversity of extracellular signals and is thus considered a key ...