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Macrophage Polarization in Leprosy-HIV Co-infected Patients
(Frontiers Media, 2020)
Immunotherapy for cancer: effects of iron oxide nanoparticles on polarization of tumor-associated macrophages
(Future Medicine Ltd, 2021)
Macrophage polarization in clinically symptomatic forms of apical periodontitis: role of lipopolysaccharide from Porphyromonas species on Toll-like receptor expression and its epigenetic regulation
(2021)
Hypothesis: The clinically symptomatic form of apical periodontitis is associated with a pro-inflammatory response and a predominant M1 macrophage polarization. This pro-inflammatory profile and the TLR2 and TLR4 expression ...
Neosaxitoxin inhibits the expression of inflammation markers of the M1 Phenotype in macrophages
(MDPI, 2020)
Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide ...
Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis
(Springer Basel Ag, 2018)
Pulmonary fibrosis is a result of an abnormal wound healing in lung tissue triggered by an excessive accumulation of extracellular matrix proteins, loss of tissue elasticity, and debit of ventilatory function. NKT cells ...
PD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8+ T cell Induced DeathPD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8+ T cell Induced Death
(Nature Publishing GroupNature Publishing Group, 2019-01)
CD8+T cells contribute to tuberculosis (TB) infection control by inducing death of infected macrophages. Mycobacterium tuberculosis (Mtb) infection is associated with increased PD-1/PD-L1 expression and alternative activation ...
High-Density-Immune-Complex Regulatory Macrophages Promote Recovery of Experimental Colitis in Mice
(Kluwer Academic/Plenum Publishers, 2022)
Transcriptional profiling of human macrophages during infection with Bordetella pertussis
(Landes Bioscience, 2020-02-19)
Bordetella pertussis, a strictly human re-emerging pathogen and the causative agent of whooping cough, exploits a broad variety of virulence factors to establish efficient infection. Here, we used RNA sequencing to analyse ...
Correlating biological activity to thermo-structural analysis of the interaction of CTX with synthetic models of macrophage membranes
(2021-12-01)
The important pharmacological actions of Crotoxin (CTX) on macrophages, the main toxin in the venom of Crotalus durissus terrificus, and its important participation in the control of different pathophysiological processes, ...