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Cytoadhesion of Plasmodium falciparum-infected erythrocytes and the infected placenta: a two-way pathway
(Associação Brasileira de Divulgação Científica, 2006)
Insulin enhances leptin expression in human trophoblastic cells
(Oxford University Press, 2013-06)
Leptin, one of the adipokines that controls energy metabolism via the central nervous system, also has pleiotropic peripheral effects, acting as a proinflammatory cytokine. Leptin is also produced by trophoblastic cells ...
Folic acid supplementation during pregnancy induces sex-specific changes in methylation and expression of placental 11β-hydroxysteroid dehydrogenase 2 in rats
(Public Library of Science, 2015)
In the placenta, 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) limits fetal glucocorticoid exposure and its inhibition has been associated to low birth weight. Its expression,
encoded by the HSD11B2 gene is regulated ...
Immunohistochemical determination of Ang-1, Ang-2 and Tie-2 in placentas of sows at 30, 60 and 114 days of gestation and validation through a bioinformatic approach
(Elsevier Science, 2018-08)
Angiopoietins (Ang-1, Ang-2) participate in vascular development and placental growth, both bind to Tie-2. This study aimed to determine the localization of angiopoietins in placental development of sows by immunohistochemistry ...
Genetic diversity of VAR2CSA ID1-DBL2Xb in worldwide Plasmodium falciparum populations: impact on vaccine design for placental malaria
(Elsevier, 2014)
In placental malaria (PM), sequestration of infected erythrocytes in the placenta is mediated by an interaction between VAR2CSA, a Plasmodium falciparum protein expressed on erythrocytes, and chondroitin sulfate A (CSA) ...
Crosstalk between estradiol and NFκB signaling pathways on placental leptin expression
(BioScientifica, 2020-07)
Pregnancy success requires a proper fetal maternal interaction at the establishment of implantation. Leptin has been described as a multitasking cytokine in pregnancy, particularly in the placenta, where it acts as an ...
MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells
(Academic Press Inc Elsevier Science, 2010-06)
Leptin, the LEP gene product, is produced in placenta where it has been found to be an important autocrine signal for trophoblastic growth during pregnancy. Thus, we have recently described the antiapoptotic and trophic ...
The term basal plate of the human placenta as a source of functional extravillous trophoblast cells
(BMC, 2014)
Background
Extravillous trophoblast (EVT) cells are of pivotal importance in human embryo implantation and homeostasis of the maternal fetal interface. Invasion of the endometrium by EVT contributes to ...
Influence of relative NK-DC abundance on placentation and its relation to epigenetic programming in the offspring
(Nature Publishing Group, 2014-08)
Normal placentation relies on an efficient maternal adaptation to pregnancy. Within the decidua, natural killer (NK) cells and dendritic cells (DC) have a critical role in modulating angiogenesis and decidualization ...
Determinación del impacto de pesticidas organofosforados sobre la placenta humana a través de modelos in vitro
(2015)
La placenta cumple funciones vitales en la gestación del ser humano. Es el órgano
que media la interrelación entre la madre y el individuo en gestación, permitiendo la
implantación y la transferencia de nutrientes, ...