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Clamidósporos do Paracoccidioides brasiliensis: isolamento e estudo da infecticidade em modelo experimental murino
(Universidade Estadual Paulista (Unesp), 2011-02-28)
Este trabalho objetivou desenvolver um protocolo para produção, isolamento e purificação de clamidósporos do P. brasiliensis (Pb) e estudar seu potencial infectante em camundongos. A cepa Bt83 foi cultivada em meio líquido ...
Estudo de indução de apoptose por Paracoccidioides brasiliensis durante a interação com células epiteliais e efeitos antiapoptóticos de substâncias naturais
(Universidade Estadual Paulista (Unesp), 2016-06-17)
Apoptosis is an important mechanism of cell regulation and several pathogens can modulate it, establishing the host infection. It was demonstrated in P. brasiliensis (Pb) and it occurs as a result of its internalization ...
Paracoccidioidal Infection in HIV Patients at an Endemic Area of Paracoccidioidomycosis in Brazil
(Springer, 2012-03-01)
The association between paracoccidioidomycosis (PCM) and AIDS is relatively rare in contrast to the higher incidence of other systemic mycosis. the explanation may be that AIDS is still predominantly an urban disease, and ...
An overview of the immunopathology of human paracoccidioidomycosis
(SPRINGER, 2008)
We review here the advances in the understanding of the immunopathology of human paracoccidioidomycosis (PCM). Its investigation must take in account the intriguing natural history of the mycosis and its agent, providing ...
Distribution of paracoccidioidomycosis: determination of ecologic correlates through spatial analyses
(Taylor & Francis Ltd, 2014)
Distribution of paracoccidioidomycosis: determination of ecologic correlates through spatial analyses
(Taylor & Francis Ltd, 2004-12-01)
Paracoccidioidomycosis (PCM) is endemic in Latin America and in countries like Brazil it carries a high mortality rate. The fungus' habitat has not been precisely determined. The present study aims to identify ecologic ...
Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis
(Blackwell Publishing, 2007-06-01)
Chloroquine, due to its basic properties, has been shown to prevent the release of iron from holotransferrin, thereby interfering with normal iron metabolism in a variety of cell types. We have studied the effects of ...
Distribution of paracoccidioidomycosis: determination of ecologic correlates through spatial analyses
(Taylor & Francis Ltd, 2004-12-01)
Paracoccidioidomycosis (PCM) is endemic in Latin America and in countries like Brazil it carries a high mortality rate. The fungus' habitat has not been precisely determined. The present study aims to identify ecologic ...
Chloroquine is therapeutic in murine experimental model of paracoccidioidomycosis
(Blackwell Publishing, 2007-06-01)
Chloroquine, due to its basic properties, has been shown to prevent the release of iron from holotransferrin, thereby interfering with normal iron metabolism in a variety of cell types. We have studied the effects of ...