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Evaluación de la integridad y funcionalidad espermática post-descongelación del caballo criollo colombiano mediante el uso de antioxidantes y un inhibidor de la capacitación.
(Universidad Nacional de ColombiaMedellín - Ciencias - Doctorado en BiotecnologíaEscuela de biocienciasFacultad de CienciasMedellínUniversidad Nacional de Colombia - Sede Medellín, 2021-08)
La criopreservación de semen equino facilita su uso en programas de inseminación artificial y mejoramiento genético, independientemente de la ubicación, disponibilidad o estado del ejemplar equino. Adicionalmente, su uso ...
PDE5 inhibition improves cardiac morphology and function in SHR by reducing NHE1 activity: Repurposing Sildenafil for the treatment of hypertensive cardiac hypertrophy
(Elsevier, 2020-11)
Previously, we have shown that an increased cGMP-activated protein Kinase (PKG) activity after phosphodiesterase 5 (PDE5) inhibition by Sildenafil (SIL), leads to myocardial Na+/H+ exchanger (NHE1) inhibition preserving ...
Adenosine A1 receptors and mitochondria: targets of remote ischemic preconditioning
(American Physiological Society, 2019-03)
Adenosine is involved in classic preconditioning in most species and acts especially through adenosine A1 and A3 receptors. The aim of the present study was to evaluate whether remote ischemic preconditioning (rIPC) activates ...
Ischemic postconditioning confers cardioprotection and prevents reduction of Trx-1 in young mice, but not in middle-aged and old mice
(Springer, 2016-04)
Thioredoxin-1 (Trx-1) is part of an antioxidant system that maintains the cell redox homeostasis but their role on ischemic postconditioning (PostC) is unknown. The aim of this work was to determine whether Trx-1 participates ...
TLR 2, TLR 4, ROS, óxido nítrico, P38 e IKK em células mononucleares de cães com leishmaniose Visceral tratadas com o imunomodulador P-MAPA: Larissa Martins Melo. -
(Universidade Estadual Paulista (Unesp), 2014-09-19)
Visceral leishmaniasis (VL) in Brazil represents a serious public health problem; therefore, it is important to study new alternatives to treat infected dogs. The immunomodulator protein aggregate magnesium-ammonium ...