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Autophagy and its impact on neurodegenerative diseases: new roles for TDP-43 and C9orf72
(Frontiers, 2017-05-30)
Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), ...
Oxidative stress in neurodegenerative diseases: Mechanisms and therapeutic perspectives
(Hindawi Publishing Corporation, 2011)
Coenzyme Q(10) and its effects in the treatment of neurodegenerative diseases
(Universidade de São Paulo (USP), Conjunto Quimicas, 2014)
The intersection between growth factors, autophagy and ER stress: A new target to treat neurodegenerative diseases?
(Elsevier Science, 2016-10-15)
One of the salient features of most neurodegenerative diseases is the aggregation of specific proteins in the brain. This proteostasis imbalance is proposed as a key event triggering the neurodegenerative cascade. The ...
The Genetic Diagnosis of Neurodegenerative Diseases and Therapeutic Perspectives
(Brain Sciences, 2018-12-13)
Genetics has led to a new focus regarding approaches to the most prevalent diseases today. Ascertaining the molecular secrets of neurodegenerative diseases will lead to developing drugs that will change natural history, ...
Pipeline for the Classification of Subjects with Neurodegenerative Diseases Based on Biomedical Signal Processing and Machine Learning Techniques
(Grupo de Investigación en Bioinstrumentación e Ingeniería Clínica (GIBIC)Medellín, 2022)
ER stress in neurodegenerative disease: from disease mechanisms to therapeutic interventions
(2017)
The conception that protein aggregates composed by misfolded proteins underlies the occurrence of several neurodegenerative diseases suggests that this phenomenon may have a common origin, ultimately driven by disruption ...