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Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles
(2012)
GLUT4-containing vesicles cycle between the plasma membrane and intracellular compartments. Insulin promotes GLUT4 exocytosis by regulating GLUT4 vesicle arrival at the cell periphery and its subsequent tethering, docking, ...
Apical Maxi-chloride channel from human placenta: 12 years after the first electrophysiological recordings
(SOCIEDAD BIOLGIA CHILE, 2006)
The Maxi-chloride channel was the first ion channel described by electrophysiological methods in placenta. Because it is difficult to access a complex epithelium such as the placenta for electrophysiological procedures, ...
Consequences of the exposure to bisphenol A in cell membrane models at the molecular level and hamster ovary cells viability
(2021-07-01)
The inadequate disposal and the difficulty in its removal from water treatment systems have made the endocrine disruptor bisphenol A (BPA) a significant hazard for humans and animals. The molecular-level mechanisms of BPA ...
Effects of cholesterol on lipid vesicle fusion mediated by infectious salmon anaemia virus fusion peptides
(2022)
Studying the variables that affect the membrane fusion mechanism of enveloped viruses is important for developing new strategies to combat viral infections. We analysed the effects of lipid vesicle cholesterol content on ...
Cholesterol modulates curcumin partitioning and membrane effects
(2018-01-01)
Curcumin, a polyphenol molecule, presents a wide range of biological activities as antioxidant, anticancer, anti-inflammatory, antimicrobial and wound healing. Although some strengths attributed to curcumin derive from ...
A closer look into the physical interactions between lipid membranes and layered double hydroxide nanoparticles
(Elsevier Science, 2020-07)
Layered double hydroxide nanoparticles (LDH-NPs) constitute promising nanocarriers for drug and gene delivery. Although their cell internalization has been studied, the interaction between LDH-NPs and biological membrane ...
Direct visualization of the lateral structure of giant vesicles composed of pseudo-binary mixtures of sulfatide, asialo-GM1 and GM1 with POPC
(Elsevier Science, 2018-02)
We compared the lateral structure of giant unilamellar vesicles (GUVs) composed of three pseudo binary mixtures of different glycosphingolipid (GSL), i.e. sulfatide, asialo-GM1 or GM1, with POPC. These sphingolipids possess ...
Extracellular vesicles and its advances in female reproduction
(2018-01-01)
Intercellular communication is an essential mechanism for development and maintenance of multicellular organisms. Extracellular vesicles (EVs) were recently described as new players in the intercellular communication. EVs ...
Hopanoid hopene locates in the interior of membranes and affects their properties
(American Chemical Society, 2021-09)
Hopanoids are proposed as sterol surrogates in some bacteria, and it has been proved that some hopanoids are able to induce a liquid-order phase state in lipid membranes. The members of this group of molecules have diverse ...