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Roscovitine use for the delay of meiotic progression in prepubertal sheep oocytes
(Empresa Brasil Pesq Agropec, 2020-01-01)
The objective of this work was to evaluate the efficiency of roscovitine on reversibly inhibiting oocytes from prepubertal sheep at the germinal vesicle (GV) stage, and to investigate the kinetics of meiosis progression ...
Time course of the meiotic arrest in sheep cumulus-oocyte complexes treated with roscovitine
(Cambridge University Press, 2015)
Temporary meiosis arrest with cyclin-dependent kinases inhibitors has been proposed in order to improve the quality of in vitro matured oocytes. In sheep, however, this phenomenon has been rarely investigated. Therefore, ...
Effect of roscovitine and cycloheximide on ultrastructure of sheep oocytes
(2013-01-01)
It is believed the temporary meiosis arrest with roscovitine or cycloheximide may improve the in vitro developmental competence of oocytes in different animal species. However, little is known about the effects of these ...
Effect of roscovitine and cycloheximide on ultrastructure of sheep oocytes
(2013-01-01)
It is believed the temporary meiosis arrest with roscovitine or cycloheximide may improve the in vitro developmental competence of oocytes in different animal species. However, little is known about the effects of these ...
Gene expression in sheep cumulus-oocyte complexes meiotically inhibited with roscovitine
(2015-01-01)
The majority of mammalian oocytes destined for in vitro maturation (IVM) have not undergone all molecular and structural changes necessary for competence acquisition to support the fertilization and early embryogenesis. ...
Time course of the meiotic arrest in sheep cumulus-oocyte complexes treated with roscovitine
(Cambridge University Press, 2015)
Time course of the meiotic arrest in sheep cumulus-oocyte complexes treated with roscovitine
(Cambridge University Press, 2015)
Prematuration of bovine oocytes with butyrolactone I reversibly arrests meiosis without increasing meiotic abnormalities after in vitro maturation
(ELSEVIER IRELAND LTD, 2009)
Objectives: Asynchrony between nuclear and cytoplasmic maturation, and possibly damage to the oocyte meiotic spindle, limits the application of in vitro maturation (IVM) in assisted reproduction. Several studies have ...
Effects of the addition of oocyte meiosis-inhibiting drugs on the expression of maturation-promoting factor components and organization of cytoplasmic organelles
(Inst Animal Reproduction Food Research, 2020-03-01)
The present study evaluated the effects of the blockade of meiosis in bovine oocytes by the cyclin-dependent kinase inhibitors roscovitine (ROS) and butyrolactone-I (BL-I) on nuclear maturation and extracellular signal-regulated ...