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Crenças atribuídas à opção de não usar MDMA (ecstasy): estudo qualitativo entre não usuários, usuários experimentais e ex-usuários
(Universidade Federal de São Paulo (UNIFESP), 2011-01-26)
Introduction: Although ecstasy (MDMA) is a drug mostly consumed in the eletronic scene context, not all individuals who faces an opportunity to use ecstasy do it. This study aimed at understanding the reasons ascribed to ...
Positive regulation of raphe serotonin neurons by serotonin 2B receptors
(Nature Publishing Group, 2018-06)
Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT2B receptors is associated with serotonin-dependent phenotypes, including impulsivity and suicidality. A lack of 5-HT2B receptors ...
Effects of group exposure on single injection-induced behavioral sensitization to drugs of abuse in mice
(Elsevier B.V., 2011-11-01)
Background: Behavioral sensitization in rodents is hypothesized to reflect neuronal adaptations that are related to drug addiction in humans. We evaluated the effects of group exposure on the acute hyperlocomotion and ...
Cromatografia quiral em escala preparativa: estudo de casos e aplicação
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Química - PPGQ, 2012-05-25)
Different types of preparative chromatography techniques were applied to the enantiomeric purification of a series of chiral drugs. The efficiency of multicolumn chromatography with variable zones (VARICOL®) process and ...