Now showing items 21-30 of 538
Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage
(Academic Press Inc. Elsevier B.V., 2011-01-01)
Telomeres are protein-DNA complexes that protect chromosome ends from degradation and fusion. In Leishmania spp., telomeric DNA comprises a conserved TTAGGG repeat and is maintained by telomerase. Telomerase is a multisubunit ...
Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds
(Elsevier B. V., 2015-08-15)
Chalcones form a class of compounds that belong to the flavonoid family and are widely distributed in plants. Their simple structure and the ease of preparation make chalcones attractive scaffolds for the synthesis of a ...
Effects of Brazilian propolis on Leishmania amazonensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2007)
Dynamic identification of H2 epitopes from Leishmania (Leishmania) amazonensis cysteine proteinase B with potential immune activity during murine infection
(John Wiley and SonsWest Sussex, 2014-02)
Peptides from the COOH-terminal extension of cysteine proteinase B from Leishmania (Leishmania) amazonensis (cyspep) can modulate immune responses in vertebrate hosts. With this hypothesis as base, we used the online ...
LaRbp38: A Leishmania amazonensis protein that binds nuclear and kinetoplast DNAs
(Elsevier B.V., 2007-07-06)
Leishmania amazonensis causes a wide spectrum of leishmaniasis. There are no vaccines or adequate treatment for leishmaniasis, therefore there is considerable interest in the identification of new targets for anti-leishmania ...
Antiprotozoal activity of the cyclopalladated complexes against leishmania amazonensis and trypanosoma cruzi
The present study describes the antiprotozoal activities of four cyclopalladated compounds, [Pd(dmba)(μ-Cl)]2 , [Pd(dmba)(NCO)(isn)], [Pd(dmba)(N3)(isn)] and [Pd(dmba)(μ-NCO)]2 , (dmba: N,N'-dimethylbenzylamine and isn: ...