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One-year treatment with gonadotropin-releasing hormone analogues does not affect body mass index, insulin sensitivity or lipid profile in girls with central precocious puberty
(De Gruyter, 2019-01-30)
Background: Puberty is associated with a physiological decline in insulin sensitivity (IS). Overweight (OW) and obesity (OB) are common among girls with central precocious puberty (CPP). CPP is considered a risk factor for ...
Low dose of insulin detemir controls glycaemia, insulinemia and prevents diabetes mellitus progression in the dog with pituitary-dependent hyperadrenocorticism
(Elsevier, 2012-08)
Diabetes is often associated with pituitary-dependent hyperadrenocorticism (PDH). Hypercortisolism causes insulin resistance and affects β-cell function. The purpose of this study was to test if daily administration of a ...
Effects of gonadotrophins and insulin on glucose uptake in the porcine cumulus–oocyte complex during IVM
(Csiro Publishing, 2019-04)
The combination of gonadotrophins (LH and FSH) and insulin is frequently used in porcine oocyte IVM, but the individual effects of gonadotrophins and insulin have not been completely studied. The aim of this study was to ...
A evolução da insulinoterapia no diabetes melito tipo 1
(Sociedade Brasileira de Endocrinologia e Metabologia, 2008-03-01)
The discovery of insulin can be considered the milestone of diabetes mellitus history and a great achievement for its treatment. The first insulin available was the regular. Afterwards, Hagedorn added the protamine to the ...
Efetividade clínica comparativa do análogo de Insulina Glargina com Insulina NPH para tratamento de pacientes com Diabetes Mellitus tipo 1
(Universidade Federal de Minas GeraisUFMG, 2015-08-03)
The insulin analogue glargine is dispensed, in the state of Minas Gerais, to patients with diabetes mellitus type 1 that attend to criteria of Health Secretariat of Minas Gerais (SESMG). Currently about 3200 patients are ...
Análogos de insulina humana versus insulina NPH para o tratamento do diabetes mellitus tipo 1: uma avaliação econômica na perspectiva do Sistema Único de Saúde.
(Universidade Federal de Minas GeraisBrasilFARMACIA - FACULDADE DE FARMACIAPrograma de Pós-Graduação em Medicamentos e Assistencia FarmaceuticaUFMG, 2022-06-09)
Type 1 diabetes mellitus (T1DM) is a chronic and costly disease both for people who live with it and for governments and society. The economic burden of T1DM is largely due to drug costs and diabetes complications. After ...