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Cytotoxic, genotoxic, and oxidative stress-inducing effect of an L-amino acid oxidase isolated from Bothrops jararacussu venom in a co-culture model of HepG2 and HUVEC cells
(2019-04-15)
Hepatocellular carcinoma incidence rates have increased worldwide, which encouraged the development of new chemotherapeutic drugs. L-Amino acid oxidases from snake venoms are cytotoxic towards human tumor cells in in vitro ...
Células endoteliais humanas (HUVEC) infectadas por Toxoplasma gondii modulam funções biológicas de células trofoblásticas extravilosas humanas (HTR-8/SVneo)Human endothelial cells (HUVEC) infected by Toxoplasma gondii change biological functions of human extravillous trophoblast cells (HTR-8/SVneo)
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Imunologia e Parasitologia Aplicadas, 2019)
Ação da vitamina D sobre a apoptose induzida por urato monossódico, peróxido de hidrogênio e fator de necrose tumoral alfa em células endoteliais de linhagem - HUVEC
(Universidade Estadual Paulista (Unesp), 2021-09-22)
Introdução: Gestações complicadas por pré-eclâmpsia (PE) estão associadas com isquemia/hipóxia placentária, estresse oxidativo, hiperuricemia e níveis elevados de citocinas pró-inflamatórias. Essas alterações fisiológicas ...
Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production
(Landes Bioscience, 2014)
Inflammatory response of endothelial cells to hepatitis C virus recombinant envelope glycoprotein 2 protein exposure
(Instituto Oswaldo Cruz, Ministério da Saúde, 2014-09-01)
The hepatitis C virus (HCV) encodes approximately 10 different structural and non-structural proteins, including the envelope glycoprotein 2 (E2). HCV proteins, especially the envelope proteins, bind to cell receptors and ...
Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production
(Landes Bioscience, 2014)
Plasma from pre-eclamptic patients induces the expression of the anti-angiogenic miR-195-5p in endothelial cells
(2016-06-01)
We examined the effect of plasma incubation from preeclampsia pregnant on the antiangiogenic miR-195-5p expression. Higher miR-195-5p expression was found in cultures incubated with preeclampsia plasma compared to those ...
Mecanismos antiangiogénicos de calreticulina de Trypanosoma cruzi
(Universidad de ChileCyberDocs, 2008)
La angiogénesis es la formación de nuevos capilares a partir de vasos preexistentes. La utilización
de agentes capaces de inhibir este proceso podría ofrecer opciones terapéuticas para patologías
dependientes del ...
Epigenetic mechanisms implicated in the programming of endothelial dysfunctión in foetuses with intrauterine growth restrictión
(2014)
The association between reduced foetal growth and adult health has risen as a feasible explanation for non-Mendelian diseases, such as hypertension and type-2 diabetes. Epigenetic mechanisms (i.e. DNA methylation, histone ...
Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high D-glucose conditions
(2019)
Diabetes mellitus type 2 (DMT2) is characterized by hyperglycemia and associated with low grade inflammation affecting both endothelial cells and monocytes. Exosomes are nanovesicles, allow communication between endothelial ...