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High rates of bovine blastocyst development after ICSI-mediated gene transfer assisted by chemical activation
(Elsevier Science Inc, 2010-10)
In order to establish conditions for intracytoplasmic sperm injection-mediated gene transfer (ICSI-MGT) in cattle, various aspects of fertilization and embryonic development were assessed after five activation treatments. ...
A new adenovector system for implementing thymulin gene therapy for inflammatory disorders
(Pergamon-Elsevier Science Ltd, 2017-07)
Thymulin is a thymic peptide possessing anti-inflammatory effects. In order to manipulate thymulin expression in gene therapy studies, we built a bidirectional regulatable two-vector Tet-Off system and the corresponding ...
Desenvolvimento de plataforma bacteriana para produção de biofármacos
(Universidade Estadual Paulista (Unesp), 2021-08-16)
A produção de biofármacos tem crescido rapidamente em todo o mundo. Porém, o processo de produção e purificação destas biomoléculas é bastante custoso. A solução para minimizar tais custos pode estar associada ao desenvolvimento ...
Connexin46 Expression Enhances Cancer Stem Cell and Epithelial-to-Mesenchymal Transition Characteristics of Human Breast Cancer MCF-7 Cells
(2021)
Connexins (Cxs) are a family of proteins that form two different types of ion channels: hemichannels and gap junction channels. These channels participate in cellular communication, enabling them to share information and ...
Ghrelin receptor signaling targets segregated clusters of neurons within the nucleus of the solitary tract
(Springer Heidelberg, 2018-09)
Ghrelin is a stomach-derived hormone that regulates a variety of biological functions such as food intake, gastrointestinal function and blood glucose metabolism, among others. Ghrelin acts via the growth hormone secretagogue ...
Focal Adhesion Dynamics Are Altered in Schizophrenia
(Society of Biological Psychiatry, 2013)
Background: Evidence from genetic association studies implicate genes involved in neural migration associated with schizophrenia
risk. Neural stem/progenitor cell cultures (neurosphere-derived cells) from olfactory mucosa ...
Connexin46 expression enhances cancer stem cell and epithelial-to-mesenchymal transition characteristics of human breast cancer mcf-7 cells
(2021-11-01)
Connexins (Cxs) are a family of proteins that form two different types of ion channels: hemichannels and gap junction channels. These channels participate in cellular communication, enabling them to share information and ...
Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
(2022-07)
Parkinson's disease is a neurodegenerative disorder that involves the death of the dopaminergic neurons of the nigrostriatal pathway and, consequently, the progressive loss of control of voluntary movements. This ...
Utilização de um repórter fluorescente para a avaliação funcional de fatores envolvidos na iniciação da tradução de tripanossomatídeos
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Genetica, 2017)
Efecto de los espectros de luz azul, roja y verde en la multiplicación celular y síntesis bioquímica de Rhodomonas spp. Y Tetraselmis spp. en condiciones in vitro.
(Facultad de Ciencias Naturales. Universidad de Guayaquil, 2016)
El crecimiento y la producción de metabolitos en microalgas de interés comercial, puede ser estimulado con variaciones en las condiciones de cultivo como la luz incidente. El establecimiento de estos protocolos puede ...