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Zebrafish as an alternative animal model in human and animal vaccination research
(Springer, 2020-05-07)
Much of medical research relies on animal models to deepen knowledge of the causes of animal and human diseases, as well as to enable the development of innovative therapies. Despite rodents being the most widely used ...
?Zebrafish as an animal model for food safety research: trends in the animal research?
(Taylor & Francis Inc, 2019-10-02)
Toxicity studies in mammals continue to be the most appropriate model for predicting risk in humans, but they tend to be expensive and time-consuming. In the aftermath of the genetic sequencing of zebrafish (Danio rerio), ...
Detection of heterozygous MDR1 nt230(del4) mutation in a mixed-breed dog: case report of possible doxorubicin toxicosis
(2013)
P-glycoprotein (ABCB1), the product of the Multidrug Resistance Gene (MDR1) (ABCB1) gene, is the major multidrug transporter contributing to the barrier function of several tissues and organs, including the brain. A four ...
Reptiles as Animal Models: Examples of their Utility in Genetics, Immunology and Toxicology
(Nova Science Publishers, 2013)
Historically, animals used as experimental models have contributed to the knowledgeof multiple aspects of organisms? biology and wildlife, providing valuable informationabout physiological processes, events, environmental ...
Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies
(SAGE Publications, 2015)
A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses ...
Evaluation of the action of a new metallic-insecticide in genetic material of Allium cepa
(Elsevier B.V., 2014-09-10)
Action of a polyamine putrescine in genetic material of Allium cepa
(Elsevier B.V., 2015-10-16)
Sensitivity of Liver Mitochondrial Functions to Various Levels of Ethanol Intake in the Rat
(1989)
Mitochondrial function appears to be an early target for ethanol toxicity, however it is not clear to what extent the effects of ethanol, which occur at levels of intake lower than those already reported in the literature, ...
Bothrops atrox from ecuadorian amazon: initial analyses of venoms from individuals
(2021)
Bothrops atrox is the most clinically relevant snake species within the Amazon region, which includes Ecuadorian
territories. It comprises a large distribution, which could contribute to the genetic and venomic ...
Rainhas Apis mellifera africanizadas tolerantes à inseticida neonicotinoideSelection queens Apis mellifera Africanized tolerant neonicotinoid insecticide
(Universidade Estadual de MaringáBrasilPrograma de Pós-Graduação em Genética e MelhoramentoUEMMaringá, PRCentro de Ciências Agrárias, 2018)