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Complimentary Diagnostic Tools for Endometrosis in Biopsies of Mares with Clinical Subfertility
(Universidade Federal do Rio Grande do Sul, 2020)
Remodelamento parenquimatoso pulmonar em dois modelos experimentais de fibrose
(Universidade Estadual Paulista (Unesp), 2012-11-21)
A fibrose pulmonar é a base patológica de uma variedade de doenças crônicas incuráveis. A IL-17A, uma glicoproteína secretada de células Th17, é uma citocina pró-fibrótica relacionada recentemente à síntese de colágeno V ...
Efeitos da exposição à sílica sobre a responsividade vascular e de vias aéreas de ratos
(Universidade Estadual Paulista (Unesp), 2011)
Silicosis, a common type of pneumoconiosis, is an occupational lung disease caused by inhalation of silica dust often with mining activity and thus reaches the miners. The fine and ultrafine silica particles deposited in ...
Erythema elevatum diutinum presenting with a giant annular pattern
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
A 45-year-old woman presented with a 3-year history of cutaneous lesions. Clinical examination revealed red-yellow to brownish infiltrated papules coalescing into annular-shaped plaques of several sizes with a hyperpigmented ...
Histological composition and progression of carotid plaque
(2007-02)
Abstract Background To analyse histological composition and progression of carotid plaque. Methods Thirty-one patients (22 males, mean age 68.03 ± 7.3 years) admitted for carotid endarterectomy for extracranial high-grade ...
Combined therapies for Duchenne muscular dystrophy to optimize treatment efficacy
(Frontiers Media, 2018-04)
Duchene Muscular Dystrophy (DMD) is the most frequent muscular dystrophy and one of the most severe due to the absence of the dystrophin protein. Typical pathological features include muscle weakness, muscle wasting, ...
Synthesis and biological evaluation of novel thiazolyl-coumarin derivatives as potent histone deacetylase inhibitors with antifibrotic activity
(MDPI AG, 2019)
New histone deacetylases (HDAC) inhibitors with low toxicity to non-cancerous cells, are a prevalent issue at present because these enzymes are actively involved in fibrotic diseases. We designed and synthesized a novel ...
Paracoccidioidomycosis: Latin America's own fungal disorder
Paracoccidioidomycosis (PCM) is a systemic, endemic fungal disorder restricted to Latin America (Mexico to Argentina); Brazil accounts for the largest number of cases. Imported cases diagnosed in North America, Europe and ...
Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis
(2016)
Fibrosis occurs in skeletal muscle under various pathophysiological conditions such as Duchenne muscular dystrophy (DMD), a devastating disease characterized by fiber degeneration that results in progressive loss of muscle ...
Hereditary equine regional dermal asthenia in three related Quarter horses in Brazil
(Blackwell Publishing, 2005-04-01)
Hereditary equine regional dermal asthenia belongs to a group of inherited, congenital connective tissue dysplasias usually described as hyperelastosis cutis, cutaneous asthenia, dermatosparaxis, or Ehlers-Danlos-like ...