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Delineation of functionally essential protein regions for 242 neurodevelopmental genes
(2022)
Neurodevelopmental disorders (NDDs), including severe paediatric epilepsy, autism and intellectual disabilities are heterogeneous conditions in which clinical genetic testing can often identify a pathogenic variant. For ...
Sunflower protein films incorporated with clove essential oil have potential application for the preservation of fish patties
(Elsevier, 2013-08)
The incorporation of sunflower protein films with clove essential oil and the application of the resulting materials on the preservation of sardine patties were studied. The addition of clove essential oil to formulations ...
Dietary Protein Intake in Elderly Women: Association With Muscle and Bone Mass
(Sage Publications Inc, 2015-04-01)
Background: An inadequate food intake, mainly with regard to protein intake, seems to contribute to a reduction of skeletal muscle and bone mass in the elderly. This study was undertaken to evaluate differences in protein ...
Mapping eIF5A binding sites for Dys1 and Lia1: In vivo evidence for regulation of eIF5A hypusination
(2003-12-18)
The evolutionarily conserved factor eIF5A is the only protein known to undergo hypusination, a unique posttranslational modification triggered by deoxyhypusine synthase (Dys1). Although eIF5A is essential for cell viability, ...
Mapping eIF5A binding sites for Dys1 and Lia1: In vivo evidence for regulation of eIF5A hypusination
(2003-12-18)
The evolutionarily conserved factor eIF5A is the only protein known to undergo hypusination, a unique posttranslational modification triggered by deoxyhypusine synthase (Dys1). Although eIF5A is essential for cell viability, ...
Protein turnover, amino acid requirements and recommendations for athletes and active populations
(Associação Brasileira de Divulgação Científica, 2012)
Skeletal muscle is the major deposit of protein molecules. As for any cell or tissue, total muscle protein reflects a dynamic turnover between net protein synthesis and degradation. Noninvasive and invasive techniques have ...
Heat shock proteins are essential components in transformation and tumor progression: Cancer cell intrinsic pathways and beyond
(Institute for Digital Multidisciplinary Publication, 2019-09)
Heat shock protein (HSP) synthesis is switched on in a remarkably wide range of tumor cells, in both experimental animal systems and in human cancer, in which these proteins accumulate in high levels. In each case, elevated ...
The Development of a Universal In Silico Predictor of Protein-Protein Interactions
(2013-05-31)
Protein-protein interactions (PPIs) are essential for understanding the function of biological systems and have been characterized using a vast array of experimental techniques. These techniques detect only a small proportion ...