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The IKK complex contributes to the induction of autophagy
(NATURE PUBLISHING GROUP, 2010-02-03)
In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...
Papel dos adrenoreceptores Beta 3 na função cardiovascular, em marcadores metabólicos e de estresse oxidativo em modelo de síndrome metabólica
(Universidade Federal de São Paulo (UNIFESP), 2019-03-28)
Objective: to analyze the role of the adrenoreceptor ß3 (ARβ3) in the Metabolic Syndrome (MS) induced by fructose consumption. Methods: CEUA/UNIFESP: 6908290716; CEUA/UPM: 151/01/2017 – male mice after weaning (21 days, ...
The role of kinin B-1 receptors in the nociception produced by peripheral protein kinase C activation in mice
(Elsevier B.V., 2008-03-01)
The peripheral injection of phorbol myristate acetate (PMA) into the mouse paw induces nociception mediated through activation of protein kinase C (PKC). in the present study, we examine the contribution of kinin B I ...
Role of kinin B1 and B2 receptors in memory consolidation during the aging process of mice
(Churchill Livingstone, 2010-04-01)
Under physiological conditions, elderly people present memory deficit associated with neuronal loss. This pattern is also associated with Alzheimer's disease but, in this case, in a dramatically intensified level. Kinin ...
Role of kinin B1 and B2 receptors in memory consolidation during the aging process of mice
(CHURCHILL LIVINGSTONE, 2010)
Under physiological conditions, elderly people present memory deficit associated with neuronal loss. This pattern is also associated with Alzheimer`s disease but, in this case, in a dramatically intensified level. Kinin ...
Pafr In Adipose Tissue Macrophages Is Associated With Anti-inflammatory Phenotype And Metabolic Homoeostasis
(PORTLAND PRESS LTDLONDON, 2016)
Adipose tissue expression of 11beta-Hydroxysteroid dehydrogenase type 1 in cushing's syndrome and in obesity
(Sociedade Brasileira de Endocrinologia e Metabologia, 2007-11-01)
Glucocorticoids have a major role in determining adipose tissue metabolism and distribution. 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) is a NADPH-dependent enzyme highly expressed in the liver and adipose ...