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Now showing items 11-20 of 123
Identification of tyrosine hydroxylase and biopterin mediating mesangial cells production of catecholamines in culture.
(Williams & Wilkins, 1997-09-01)
Unraveling the role of the tyrosine tetrad from the binding site of the epigenetic writer MLL3 in the catalytic mechanism and methylation multiplicity
(MDPI, 2022)
MLL3, also known as KMT2C, is a lysine mono-methyltransferase in charge of the writing of an epigenetic mark on lysine 4 from histone 3. The catalytic site of MLL3 is composed of four tyrosines, namely, Y44, Y69, Y128, and ...
A Comparative Meta-Analysis and in silico Analysis of Differentially Expressed Genes and Proteins in Canine and Human Bladder Cancer
(2020-11-16)
Canine and human bladder cancer present similar anatomical, morphological, and molecular characteristics, and dogs can be considered a model for human bladder cancer. However, the veterinary literature lacks information ...
Characterisation of tyrosine-phosphorylation-defective calmodulin mutants
(Protein Expression and PuriWcation, 2017)
Nickel(II) complexes based on L-amino-acid-derived ligands: Synthesis, characterization and study of the role of the supramolecular structure in carbon dioxide capture
(International Union of Crystallography, 2020-09)
The formation of the symmetrical 3-carbonate-bridged self-assembled trinuclear NiII complex Na2{[Ni(LO)2(H2O)]3(3-CO3)} (LO is the carboxylate anion of a l-tyrosine derivative), involves atmospheric CO2 uptake. The asymmetric ...
Imatinib mesylate alters the expression of genes related to disease progression in an animal model of uveal melanoma
(Ios Press, 2011-01-01)
Imatinib mesylate (IM) is a compound that inhibits both BCR-ABL tyrosine kinase and c-kit receptors. Tyrosine kinases are important in cellular signaling and mediate major cellular processes such as proliferation, ...
Cell-cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris
(NATL ACAD SCIENCES, 2010)
RpfG is a paradigm for a class of widespread bacterial two-component regulators with a CheY-like receiver domain attached to a histidine-aspartic acid-glycine-tyrosine-proline (HD-GYP) cyclic di-GMP phosphodiesterase domain. ...
The role of thyroglobulin in thyroid hormonogenesis
(Springer, 2019-06)
In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of thyroglobulin is conserved in all vertebrates. ...