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Pixuna virus modifies host cell cytoskeleton to secure infection
(Nature Publishing Group, copyright 2011-, 2017-07-18)
Pixuna virus (PIXV) is an enzootic member of the Venezuelan Equine Encephalitis Virus complex and belongs to the New World cluster of alphaviruses. Herein we explore the role of the cellular cytoskeleton during PIXV ...
RNA interference of Marlin-1/Jakmip1 results in abnormal morphogenesis and migration of cortical pyramidal neurons
(2012)
The formation of the nervous systems requires processes that coordinate proliferation, differentiation and migration of neuronal cells, which extend axons, generate dendritic branching and establish synaptic connections ...
Contribution of NADPH oxidase to the establishment of hippocampal neuronal polarity in culture
(Company of Biologists Ltd., 2015)
Reactive oxygen species (ROS) produced by the NADPH oxidase (NOX) complex play
important physiological and pathological roles in neurotransmission and neurodegeneration,
respectively. However, the contribution of ROS to ...
Neuronal protein trafficking: Emerging consequences of endoplasmic reticulum dynamics
(2011)
The highly polarized morphology and complex geometry of neurons is determined to a great extent by the structural and functional organization of the secretory pathway. It is intuitive to propose that the spatial arrangement ...
Trypanosoma cruzi trypomastigotes induce cytoskeleton modifications during HeLa cell invasion
(Instituto Oswaldo Cruz, Ministério da Saúde, 2011-12-01)
It has been recently shown that Trypanosoma cruzi trypomastigotes subvert a constitutive membrane repair mechanism to invade HeLa cells. Using a membrane extraction protocol and high-resolution microscopy, the HeLa ...
Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Schizophrenia is likely to be a consequence of serial alterations in a number of genes that, together with environmental factors, will lead to the establishment of the illness. The dorsolateral prefrontal cortex (Brodmann`s ...
ARF6, PI3-kinase and host cell actin cytoskeleton in Toxoplasma gondii cell invasion
(Elsevier B.V., 2009-01-16)
Toxoplasma gondii infects a variety of different cell types in a range of different hosts. Host cell invasion by T. gondii occurs by active penetration of the host cell, a process previously described as independent of ...