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Antiproliferative effect of triclabendazole and clofazimine on Toxoplasma gondii growth, a repurposing approach
(Fundación Revista Medicina, 2019)
Toxoplasmosis is an infection caused by the parasite Toxoplasma gondii. Although healthy individuals present few symptoms, the disease could have a high impact in immunocompromised individuals and in congenital infection, ...
Ensaio clínico duplo-cego controlado e randômico, comparando a eficácia da Clofazimina com a Cloroquina, no tratamento das lesões cutâneas do Lúpus Eritematoso Sistêmico
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Ciências da SaúdeCiências da Saúde, 2007-06-22)
PURPOSE: To evaluate the capacity of clofazimine (CFZ) to control cutaneous activity of systemic lupus erythematosus (SLE), compared with chloroquine diphosphate (CDP).
METHODS: A prospective, randomized, controlled, ...
Eritema nudoso leproso persistente y enteropatía letal por clofazimina
(Biomédica, 2009)
Introducción. La enteropatía por clofazimina es una complicación grave de este fármaco, cuando
se usa a dosis altas para la reacción leprosa tipo 2 y otras enfermedades.
Objetivo. Presentar una mujer de 31 años con síntomas ...
Leprosy: current situation, clinical and laboratory aspects, treatment history and perspective of the uniform multidrug therapy for all patients
(Sociedade Brasileira de Dermatologia, 2020)
Double-blind, randomized, controlled clinical trial of clofazimine compared with chloroquine in patients with systemic lupus erythematosus
(Wiley-Blackwell, 2005-10-01)
Objective. To evaluate the efficacy of clofazimine (CFZ) compared with chloroquine diphosphate (CDP) for the treatment of cutaneous involvement in systemic lupus erythematosus (SLE).Methods. A prospective, randomized, ...
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach
(Sociedade Brasileira de Dermatologia, 2020)
Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease
(Elsevier France-editions Scientifiques Medicales Elsevier, 2019-10)
Current treatment for Chagas disease is limited to Benznidazole andNifurtimox which present side effects and limited efficacy at the chronicstage of disease. This underscores the need for novel therapeuticapproaches ...