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Distribution of a Robertsonian translocation in goats
(1992-09-01)
Two hundred and five animals were cytogenetically studied. They were related to a male goat called 'Harald', imported from Switzerland, who was a t 5 15 chromosomic translocation carrier. 29.27% of the analyzed animals ...
Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs deficient context
(Springer, 2015-12)
Etoposide (ETO), a drug used for the treatment of human tumors, is associated with the development of secondary malignancies. Recently, therapeutic strategies have incorporated chemosensitizing agents to improve the tumoral ...
Alteraciones cromosómicas en trabajadores ocupacionalmente expuestos a radiación ionizante del Hospital Provincial General Docente de Riobamba (HPGDR)
(Escuela Superior Politécnica de Chimborazo, 2020-02-27)
The purpose of this research was to determine the chromosomal alterations caused by exposure to low-dose ionizing radiation at the General Teaching Provincial Hospital of Riobamba. It was carried out in compliance with the ...
Daño genético persistente inducido por venenos de topoisomerasa II en fibroblastos humanos normales: generación de inestabilidad cromosómicaPersistent genetic damage induced by topoisomerase II poisons in normal human fibroblasts: generation of chromoso me instability
(Sociedad Argentina de Genética, 2016-12)
Topoisomerase II (Top2) poisons idarubicin (IDA) and etoposide (ETO) are anticancer drugs that target Top2 stabilizing DNA-enzymecomplexes and generating double-strand breaks (DSB). These DNA lesions are dangerous because ...
Roles of nibrin and ATM/ATR kinases on the G2 checkpoint under endogenous or radio-induced DNA damage
(Sociedad de Biología de Chile, 2005)
Biodegradability and toxicity assessment of bleach plant effluents treated anaerobically
(IWA PUBLISHING, 2010)
As part of an experimental project on the treatment of bleach plant effluents the results of biodegradability and toxicity assessment of effluents from a bench-scale horizontal anaerobic immobilized bioreactor (HAIB) are ...
Cytogenetic alterations in field workers routinely exposed to pesticides in Bogota flowers farms
Frequency of cytogenetic alterations (micronuclei and chromosome aberrations), DNA repairdeficiencies and acetylcholinesterase activity was determined for field workers in Bogotá,Colombia. These workers were regularly ...
Prognostic Implications of Cytogenetic Features in Myelodysplastic Syndromes
(London Touch Briefing, 2013-01)
Myelodysplastic Syndromes (MDS) are a heterogeneous group of hematological diseases characterized by refractory cytopenia(s) and variable risk of leukemic progression. Cytogenetic analysis is important in day-to-day clinical ...
Allium cepa test in environmental monitoring: A review on its application
(Elsevier B.V., 2009-07-01)
Higher plants are recognized as excellent genetic models to detect environmental mutagens and are frequently used in monitoring studies. Among the plant species, Alium cepa has been used to evaluate DNA damages, such as ...