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Efectos de la exposición prenatal al agonista cannabinoide WIN55,212-2 sobre la proliferación, la migración y el citoesqueleto neuronal de la rataEffect of prenatal exposure to the cannabinoide receptor agonist WIN55,212-2 on neuronal proliferation, migration and neuronal cytoskeleton in the cerebral cortex of the rat
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2012)
Further evidence for the neuroplastic role of cannabinoids: a study in organotypic hippocampal slice cultures
(Springer, 2015-08)
Endocannabinoid receptors CB1R and CB2R are present in the CNS and modulate synaptic activity. By using an in vitro model, two concentrations of CB1R agonist ACEA at 0.5 and 5 μM doses and CB1R antagonist AM251 at 1 and ...
Uso terapéutico de cannabinoides bajo prescripción médica
(Colegio de Médicos y Cirujanos de Costa Rica, 2007)
Artificial Neural Networks and the Study of the Psychoactivity of Cannabinoid Compounds
(WILEY-BLACKWELL, 2010)
Cannabinoid compounds have widely been employed because of its medicinal and psychotropic properties. These compounds are isolated from Cannabis sativa (or marijuana) and are used in several medical treatments, such as ...
Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.
(Elsevier Science, 2017-11)
Cannabis sativa L. extracts with high concentration of δ9-tetrahydrocannabinolic acid (THCA) and δ9-tetrahydrocannabinol (THC) were obtained by supercritical carbon dioxide (CO2) extraction. The objective of this work was ...
The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data
(Assoc Brasileira Psiquiatria, 2017)
Objective: Schizophrenia is a multifactorial disorder. It is known that a combination of extensive multiple common alleles may be involved in its etiology, each contributing with a small to moderate effect, and, possibly, ...
Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles-A New Family of High Affinity CB1 Cannabinoid Ligands
(2013)
A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 ...