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Mostrando ítems 11-20 de 84
Antiproliferative activity, isolation and identification of active compound from Gaylussacia brasiliensis
(Soc Brasileira FarmacognosiaJoao PessoaBrasil, 2011)
Topoisomerase I inhibitor, camptothecin, induces apoptogenic signaling in human embryonic stem cells
(Elsevier, 2013-12)
Embryonic stem cells (ESCs) need to maintain their genomic integrity in response to DNA damage to safeguard the integrity of the organism. DNA double strand breaks (DSBs) are one of the most lethal forms of DNA damage and, ...
Caracterização da atividade da HJURP na redução do estresse replicativo de linhagens de glioblastoma
(Universidade Estadual Paulista (Unesp), 2018-10-31)
O câncer é um conjunto de alterações celulares que favorecem a proliferação descontrolada e a aquisição de propriedades metastáticas. A ativação de oncogenes e/ou a perda de genes supressores tumorais leva a desbalanços ...
Camptothecin induces the transit of fASl trimers to the cell surface in apoptotic heP-2 cells
(Springer Nature, 2006-04-19)
Fas ligand (L) is a membrane protein from the tumor necrosis factor
(TNF) family. It induces apoptosis upon contact with its Fas/CD95/APO1
receptor. Trimerization of FasL on the surface of effector cells is essential in ...
Oxidative stress, superoxide production, and apoptosis of neutrophils in dogs with chronic kidney disease
(2013-04-01)
Oxidative stress is a key component in the immunosuppression of chronic kidney disease (CKD), and neutrophil function may be impaired by oxidative stress. To test the hypothesis that in uremic dogs with CKD, oxidative ...
Oxidative stress, superoxide production, and apoptosis of neutrophils in dogs with chronic kidney disease
(2013-04-01)
Oxidative stress is a key component in the immunosuppression of chronic kidney disease (CKD), and neutrophil function may be impaired by oxidative stress. To test the hypothesis that in uremic dogs with CKD, oxidative ...