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Multiple-time-scale framework for understanding the progression of Parkinson's disease
(American Physical Society, 2014-12)
Parkinson's disease is marked by neurodegenerative processes that affect the pattern of discharge of basal ganglia neurons. The main features observed in the parkinsonian globus pallidus pars interna (GPi), a subdomain of ...
AGE-RELATED ANTICONVULSANT ACTIVITY of NMDA in the RAT CAUDATE-PUTAMEN
(Elsevier B.V., 1992-06-19)
Striatal pathways are important for modulating the threshold for seizures in the rat forebrain. N-Methyl-D-aspartate (NMDA), an excitatory amino acid derivative and powerful anticonvulsant agent, when injected into the ...
Fronto-subcortical circuits for cognition and motivation: Dissociated recovery in a case of loss of psychic self-activation
(Frontiers Media S.A., 2019)
In humans and non-humans primates, extensive evidence supports the existence of subcortico-cortical circuits for cognition and behavior. Lesions studies are critical to understand the clinical significance of these ...
Obstacle circumvention and eye coordination during walking to least and most affected side in people with Parkinson's disease
(2018-07-02)
Background: The mechanisms that contribute to gait asymmetry in people with Parkinson's disease (PD) are unclear, mainly during gait with greater environmental demand, such as when an obstacle is circumvented while walking. ...
Fronto-Subcortical Circuits for Cognition and Motivation: Dissociated Recovery in a Case of Loss of Psychic Self-Activation
(Frontiers Ed., 2019-01)
In humans and non-humans primates, extensive evidence supports the existence of subcortico-cortical circuits for cognition and behavior. Lesions studies are critical to understand the clinical significance of these ...
PARADOXICAL ANTICONVULSANT ACTIVITY of the GAMMA-AMINOBUTYRATE ANTAGONIST BICUCULLINE METHIODIDE in the RAT STRIATUM
(Wiley-Blackwell, 1991-01-01)
Bicuculline methiodide (BMI), a gamma-aminobutyrate (GABA) antagonist, is a powerful convulsant agent when injected into the cerebral ventricles, amygdala, hippocampus, thalamus, neocortex, and deep prepiriform cortex in ...
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries
(1993)
A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries
(1993)
A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
Behavioral indices of moderate nigrostriatal 6–hydroxydopamine lesion: a preclinical Parkinson's model.
(1993-02)
Asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6-hydroxydopamine into the substantia nigra. Animals with severe lesions, ...