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Differential response of myeloid-derived suppressor cells to the nonsteroidal anti-inflammatory agent indomethacin in tumor-associated and tumor-free microenvironments
(American Association of Immunologists, 2015-04-01)
Myeloid-derived suppressor cells (MDSCs) are key regulatory cells that control inflammation and promote tumor-immune escape. To date, no specific immunomodulatory drug has proven efficacy in targeting the expansion and/or ...
Anti-inflammatory activity of Lychnophora passerina, Asteraceae (Brazilian arnica)
(2011-05-17)
Ethnopharmacological relevance: Lychnophora passerina (Asteraceae), popularly known as arnica, is used to treat inflammation, pain, rheumatism, contusions, bruises and insect bites in Brazilian traditional medicine. Materials ...
Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape
(2007)
The role of cytokines in modulating the formation of new tumors is mediated by their ability to regulate antigen-specific anti-tumor responses and by the activation of non-specific mechanisms, including those involved in ...
A novel immunomodulatory hemocyanin from the limpet fissurella latimarginata promotes potent anti-tumor activity in melanoma
(PUBLIC LIBRAY OF SCIENCE, 2014)
Human Survivin and Trypanosoma cruzi Calreticulin Act in Synergy against a Murine Melanoma In Vivo
(2014)
Immune-based anti-tumor or anti-angiogenic therapies hold considerable promise for the treatment of cancer. The first approach seeks to activate tumor antigen-specific T lymphocytes while, the second, delays tumor growth ...
Human survivin and trypanosoma cruzi calreticulin act in synergy against a murine melanoma in vivo
(2014)
Immune-based anti-tumor or anti-angiogenic therapies hold considerable promise for the treatment of cancer. The first
approach seeks to activate tumor antigen-specific T lymphocytes while, the second, delays tumor growth ...
SLPI (secretory leukocyte peptidase inhibitor)
(University Hospital of Poitiers, 2015-08)
Secretory Leukocyte Peptidase Inhibitor (SLPI) functionality in health and disease: Secretory Leukocyte Peptidase Inhibitor (SLPI) is a serine protease inhibitor of cathepsin G, trypsin and chymotrypsin, but primarily ...