Buscar
Mostrando ítems 4701-4710 de 10350
Isozymatic and morphological diversity in the races of maize of Mexico
(2000)
To determine the relationships and genetic diversity among the Mexican races of maize, 209 accessions representing 59 races were analyzed for 21 enzyme systems encoded by 37 loci; 154 out of the 209 accessions were grown ...
Isozymatic and morphological diversity in the races of maize of Mexico
(2000)
To determine the relationships and genetic diversity among the Mexican races of maize, 209 accessions representing 59 races were analyzed for 21 enzyme systems encoded by 37 loci; 154 out of the 209 accessions were grown ...
ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in chileans
(Elsevier, 2020)
BACKGROUND: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
How natural selection shapes genetic differentiation in the MHC region: A case study with Native Americans
(Elsevier, 2021)
The Human Leukocyte Antigen (HLA) loci are extremely well documented targets of balancing selection, yet few studies have explored how selection affects population differentiation at these loci. In the present study we ...
Caracterización genotípica por MLST de Ornithobacterium rhinotracheale procedentes de aves de corral en el Perú
(Facultad de Medicina Veterinaria. Universidad Nacional Mayor de San Marcos, 2021)
The aim of this study was the genotyping of Ornithobacterium rhinotracheale. For this, 36 strains were identified by molecular testing and genotyping was performed by Multilocus Sequence Typing (MLST). The tests identified ...
Genetic analysis of hereditary ataxias in Peru identifies SCA10 families with incomplete penetrance
(Springer, 2020)
Relative frequency of hereditary ataxias remains unknown in many regions of Latin America. We described the relative frequency in spinocerebellar ataxias (SCA) due to (CAG)n and to (ATTCT)n expansions, as well as Friedreich ...
Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Brazil
(Springer Nature, 2022)
As whole-genome sequencing (WGS) becomes the gold standard tool for studying population genomics and medical applications, data on diverse non-European and admixed individuals are still scarce. Here, we present a high-coverage ...
Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort
(Elsevier, 2022)
Background: Large-scale Parkinson's disease (PD) genome-wide association studies (GWAS) have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed ...
NAToRA, a relatedness-pruning method to minimize the loss of dataset size in genetic and omics analyses
(Elsevier, 2022)
Genetic and omics analyses frequently require independent observations, which is not guaranteed in real datasets. When relatedness cannot be accounted for, solutions involve removing related individuals (or observations) ...
Nyssorhynchus darlingi genome-wide studies related to microgeographic dispersion and blood-seeking behavior
(BioMed Central, 2022)
Background: In Brazil, malaria is concentrated in the Amazon Basin, where more than 99% of the annual cases are reported. The main goal of this study was to investigate the population structure and genetic association of ...