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A comprehensive characterization of cell cultures and xenografts derived from a human verrucous penile carcinoma
(2016-08-01)
This study aimed to establish and characterize primary cell cultures and xenografts derived from penile carcinoma (PeCa) in order to provide experimental models for cellular processes and efficacy of new treatments. A ...
Combined methods to evaluate human cells in muscle xenografts
(Public Library of Science, 2019)
Preclinical platform of retinoblastoma xenografts recapitulating human disease and molecular markers of dissemination
(Elsevier Ireland, 2016-09)
Translational research in retinoblastoma – a pediatric tumor that originates during the development of the retina – would be improved by the creation of new patient-derived models. Using tumor samples from enucleated eyes ...
Exploiting zebrafish xenografts for testing the in vivo antitumorigenic activity of microcin E492 against human colorectal cancer cells
(Frontiers Media, 2020)
One of the approaches to address cancer treatment is to develop new drugs not only to obtain compounds with less side effects, but also to have a broader set of alternatives to tackle the resistant forms of this pathology. ...
Effect of curcumin on pro-angiogenic factors in the xenograft model of breast cancer
(2015-12-01)
The formation of a new blood vessel is stimulated by angiogenic factors. Curcumin, which is the active ingredient of the spice plant Curcuma longa L and is used as food and traditional medicine, has shown anticancer effects ...
In vitro and in vivo antitumor effects of the VO-chrysin complex on a new three-dimensional osteosarcoma spheroids model and a xenograft tumor in mice
(Springer, 2016-10)
Osteosarcoma (OS) is the most common primary tumor of bone, occurring predominantlyin the second decade of life. High-dose cytotoxic chemotherapy and surgical resection haveimproved prognosis, with long-term survival for ...
Comparative histomorphometric and tomographic analysis of maxillary sinus floor augmentation in rabbits using autografts and xenografts
(WILEY-LISS, 2008)
Our goal was to evaluate bone neoformation promoted by a bovine xenograft composite (XC) compared with autogenous graft for maxillary sinus augmentation in a rabbit model. The left maxillary sinus of 18 male rabbits was ...
The growth of glioblastoma orthotopic xenografts in nude mice is directly correlated with impaired object recognition memory
(Elsevier ScienceNew York, 2014-01-17)
Cognitive dysfunction is found in patients with brain tumors and there is a need to determine whether it can be replicated in an experimental model. In the present study, the object recognition (OR) paradigm was used to ...
Presence of human breast cancer xenograft changes the diurnal profile of amino acids in mice
(2022-12-01)
Human xenografts are extremely useful models to study the biology of human cancers and the effects of novel potential therapies. Deregulation of metabolism, including changes in amino acids (AAs), is a common characteristic ...