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Viral silencing suppressors and cellular proteins partner with plant RRP6-like exoribonucleases
(Springer, 2020-10)
RNA silencing and RNA decay are functionally interlaced, regulate gene expression and play a pivotal role in antiviral responses. As a counter defensive strategy, many plant and mammalian viruses encode suppressors which ...
Identification and characterization of two RNA silencing suppressors encoded by ophioviruses
(Elsevier Science, 2017-05)
Citrus psorosis virus and Mirafiori lettuce big-vein virus are two members of the genus Ophiovirus, family Ophioviridae. So far, how these viruses can interfere in the antiviral RNA silencing pathway is not known. In this ...
The role of myeloid-derived suppressor cells in chronic infectious diseases and the current methodology available for their study
(2019)
An effective pathogen has the ability to evade the immune response. The strategies used to achieve this may be based on the direct action of virulence factors or on the induction of host factors. Myeloid-derived suppressor ...
The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53
(Elsevier Science BvAmsterdamHolanda, 2005)
Folding of a cyclin box: linking multitarget binding to marginal stability, oligomerization, and aggregation of the retinoblastoma tumor suppressor AB pocket domain
(American Society For Biochemistry And Molecular Biology, 2013-06)
The retinoblastoma tumor suppressor (Rb) controls the proliferation, differentiation, and survival of cells in most eukaryotes with a role in the fate of stem cells. Its inactivation by mutation or oncogenic viruses is ...
The role of myeloid-derived suppressor cells in chronic infectious diseases and the currentmethodology available for their study
(2019)
An effective pathogen has the ability to evade the immune response. The strategies used to achieve this may be based on the direct action of virulence factors or on the induction of host factors. Myeloid-derived suppressor ...
E6AP goes viral: the role of E6AP in viral- and non-viral-related cancers
(Oxford University Press, 2019)
Since its discovery, the E3 ubiquitin ligase E6-associated protein (E6AP) has been studied extensively in two pathological contexts: infection by the human papillomavirus (HPV), and the neurodevelopmental disorder, Angelman ...